Release Date:  April 29, 1999


National Cancer Institute

The National Cancer Institute (NCI) announces a new initiative: Rapid Access to
Preventive Intervention Development (RAPID).  RAPID will make available to
academic investigators the preclinical and early clinical drug development
contract resources of NCI's Division of Cancer Prevention. The goal of RAPID is
the rapid movement of novel molecules and concepts from the laboratory to the
clinic for clinical trials of efficacy.  RAPID will assist investigators who
submit successful requests by providing any (or all) of the pre-clinical and
phase 1 clinical developmental requirements for phase 2 clinical efficacy trials.
These include, for example, preclinical pharmacology, toxicology, and efficacy
studies;  bulk supply, GMP manufacturing, and formulation;  and regulatory and
IND support and phase 1 clinical studies.  Suitable types of agents for RAPID may
range from single chemical or biological entities to defined complex mixtures
with the potential to prevent, reverse, or delay carcinogenesis.  For more
detailed information, visit the web site, http://dcp.nci.nih.gov/CB/

Requests for RAPID resources are to be submitted as described in the web site. 
Written requests will be evaluated by a specially constituted RAPID panel,
consisting of selected NCI staff and outside experts from academia and industry. 
Requests must be received on or before November 1, 1999.  Requests  should be
submitted directly to the office listed below.


Inquiries are encouraged, and the opportunity to clarify issues or questions is

Please contact:

James A. Crowell, Ph.D.
Division of Cancer Prevention
National Cancer Institute
6130 Executive Boulevard, Suite 200B
Bethesda, MD  20892
Rockville, MD 20852 (for express/courier service)
Telephone:  (301) 594-0459
FAX:  (301) 402-0553, (301) 594-2943
Email:  jc94h@nih.gov

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