Key Dates
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National Center for Advancing Translational Sciences (NCATS)
The National Center for Advancing Translational Sciences (NCATS) intends to publish a Funding Opportunity Announcement (FOA) to advance the diagnosis, management, and treatment of rare diseases). The Rare Diseases Clinical Research Network (RDCRN) consists of the Rare Diseases Clinical Research Consortia (RDCRC) that promote highly collaborative, multi-site, patient-centric, translational, and clinical research and the Data Management and Coordinating Center (DMCC), which will facilitate and support the activities of each of the Rare Diseases Clinical Research Consortia (RDCRC) along with trans-network activities that broadly facilitate the advancement of rare disease research.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.
The FOA is expected to be published in 2024, with an estimated award date in 2025. This FOA will utilize the U2Cactivity code, which supports specialized centers through multi-project cooperative agreement awards to support research activities with substantial involvement from NIH program staff. Details of the planned FOA are provided below.
The Rare Diseases Clinical Research Network (RDCRN) is a cooperative network composed of multiple Rare Diseases Clinical Research Consortia (RDCRC) and a Data Management and Coordinating Center (DMCC) to facilitate clinical research in rare diseases carried out by the RDCRCs.
The DMCC will consist of:
- Administrative Core – Provides support for individual RDCRC as well as the RDCRN as a whole.
- Data Management Core – In collaboration with the RDCRCs provide support for Data Management and Data Sharing with the broad research community
- Clinical Research Core – Provide expertise and consulting providing expertise and consulting to the RDCRCs in areas including, but not limited to, Protocol Development and Management, Biostatistics, Study Designs and Regulatory Requirements.
- Engagement and Administrative Core - Working collaboratively with the RDCRCs and the Coalition of Patient Advocacy Groups (CPAG), the Engagement and Dissemination Core will develop a broad RDCRN outreach plan for the consortium. The outreach will extend to basic and clinical researchers, academic and practicing physicians, patients, and the general public. The core will provide an internet-based web-portal to serve as a central access point to information generated by the RDCRCs.
TBD
~$1M/ direct cost per year (maximum 5-year duration of grant)
Dependent on funds available
TBD
TBD
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government
Applications are not being solicited at this time.
Please direct all inquiries to:
Tiina K. Urv, Ph.D.
National Center for Advancing Translational Sciences (NCATS)
301-827-2746
and Human Services (HHS)
