Notice of Modifications to PAR-15-172 to Allow for Resubmissions and to Expand the List of High Priority Translational Research Opportunities

Notice Number: NOT-TR-16-003

Key Dates
Release Date:   December 15, 2015

Related Announcements

Issued by
National Center for Advancing Translational Sciences (NCATS)


The purpose of this Notice is make modifications for PAR-15-172 to allow for resubmissions and to expand the list of high priority translational research opportunities.    

Section I. Funding Opportunity Description

PAR-15-172 supports applications for innovative collaborative investigations (involving three or more CTSA sites) into improvements of the methods of translational research, at any step in the translational spectrum (T1-T4).  It is anticipated that the combined effort of three or more CTSA hubs in flexible networks will substantially enhance the effectiveness of the CTSA consortium to address high priority translational research questions.  PAR-15-172 therefore aims to support innovative and collaborative experimental translational research projects carried out in the CTSA consortium.  Below is an additional high priority translational research area suitable for this FOA:

  • Utilizing microphysiological systems (or organs on chips) in translational initiatives including drug discovery, novel mechanisms in disease models (including rare disease), refined and well-characterized iPSC tissues for TC systems, multi-organ system integration and personalized “you-on-a-Chip” technology.  Microphysiological systems are defined as devices containing scaffolding, mechanical factors (ex. perfusion, stretch) and multi-cellular tissues that recapitulate physiological environments. 

Part 2. Section II. Award Information

Currently reads: 

Application Types Allowed


The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types.


Modified to read: 

Application Types Allowed


The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types.


Section V. Application Review Information: 
Additional review criteria

Add the following text:

For Resubmissions, the committee will evaluate the application as now presented, taking into consideration the responses to comments from the previous scientific review group and changes made to the project.

All other aspects of this FOA remain the same.


Please direct all inquiries to:

Philip J. Brooks, Ph.D.
National Center for Advancing Translational Sciences (NCATS)
Telephone: 301-443-0513