Notice Announcing the NIH Common Fund Data Ecosystem (CFDE) Training Center (OT2)
Notice Number:

Key Dates

Release Date:

February 12, 2024

Related Announcements


Issued by

Office of Strategic Coordination (Common Fund)


This Notice announces the publication of a new Research Opportunity Announcement (ROA), NIH Common Fund Data Ecosystem (CFDE) Training Center and the key dates related to this opportunity. The ROA was released on the NIH Common Fund website (See OTA-24-004).

Informational Webinar Date: February 16, 2024, 2:00-3:00pm Eastern Time (See CFDE Frequently Asked Questions for more information).

Letter of Intent (LOI) Due Date (Optional): March 1, 2024 by 5:00 PM local time of applicant organization.

Proposal Due Date: April 1, 2024 by 5:00 PM local time of applicant organization. Late applications to this ROA will not be accepted.

The Common Fund Data Ecosystem (CFDE) is an infrastructure investment made by the Common Fund to address the growing challenges facing scientific programs that leverage data-intensive strategies. To support these programs and downstream data users, the CFDE is helping to ensure that all Common Fund data sets are Findable, Accessible, Interoperable, and Reusable (FAIR), providing training for users to operate on the data in a cloud environment, and ensuring that Common Fund data continue to be available after individual programs are completed. The CFDE will amplify the impact of many Common Fund programs by enabling researchers to interrogate disparate data sets, thereby making new kinds of scientific discoveries that are otherwise unattainable.

The purpose of this announcement is to invite applications to establish the Training Center for the CFDE. The Training Center award made through this announcement will support the CFDE by providing and evaluating training that enables the research community, with a special emphasis on postgraduate students engaged in research and early stage investigators, to use data sets and knowledge generated by Common Fund programs. The Training Center will work collaboratively with other participating components of the CFDE to support and coordinate training-related activities across the ecosystem.

The Training Center will promote the use and reuse of Common Fund resources by creating and implementing activities addressing three target functions: 1) Training activities – Provide needed training and professional mentoring to new users of Common Fund data; 2) Coordination – Coordinate infrastructure and activities into a cohesive ecosystem serving a broad and diverse biomedical research community; and 3) Web infrastructure – Provide a web infrastructure to enable users to query across and use multiple Common Fund data sets and connect with other users virtually. 

Unlocking the full potential of Common Fund resources through expanded use and reuse will require expertise from multiple scientific domains, including biomedicine, data science, data management, and cloud workspace training. Applicants responding to this ROA are expected to familiarize themselves with the other components of the CFDE described in the ROA, as the Training Center will be expected to communicate, coordinate, and collaborate with these components.

An Informational Webinar will be held for potential applicants from 2-3pm Eastern Time on Friday, February 16, 2024. Registration information for the Webinar and additional information on the ROA are posted on the CFDE Frequently Asked Questions website: Materials from the Webinar will be made available on that website for those unable to attend.

Award Information

The Common Fund anticipates making one award to establish the CFDE Training Center. The Common Fund may allocate up to $1,200,000 for the first-year total (direct + indirect costs for this center, up to $1,200,000 for year two, and up to $1,000,000 per year for years 3-5. This award is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Future year amounts will depend on annual appropriations. 

Eligibility Information

Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. 

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. 

Foreign components, as defined in the NIH Grants Policy Statement, are allowed. 

The following entities are eligible to apply under this ROA:  

Higher Education Institutions 

  • Public/State Controlled Institutions of Higher Education
  • Private Institutions of Higher Education 

The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education: 

  • Hispanic-serving Institutions 
  • Historically Black Colleges and Universities (HBCUs) 
  • Tribally Controlled Colleges and Universities (TCCUs) 
  • Alaska Native and Native Hawaiian Serving Institutions 
  • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs) 

Nonprofits Other Than Institutions of Higher Education

  • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • Faith-based or Community-based Organizations
  • Regional Organizations 

For-Profit Organizations

  • Small Businesses 
  • For-Profit Organizations (Other than Small Businesses) 


  • State Governments 
  • County Governments
  • City or Township Governments
  • Special District Governments
  • American Indian/Native American Tribal Governments (Federally Recognized)
  • American Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Eligible Agencies of the Federal Government
  • U.S. Territory or Possession 


  • Independent School Districts
  • Native American Tribal Organizations (other than Federally recognized tribal governments) 

Responsiveness Criteria

Applications deemed non-responsive will not proceed to review. The following are considered non-responsive for this ROA:

  • Applications submitted from organizations not included in the Eligibility section (see Section 3 in the ROA). 
  • Applications without an Enhancing Educational Inclusivity Plan (see Section 8.3 in the ROA).
  • Applications without a Recruitment Plan to Enhance Diversity (see Section 8.3 in the ROA). 


Please direct all inquiries to:

Sahana N. Kukke, PhD 

George Papanicolaou, PhD