Request for Information: NIH Common Fund is Soliciting Ideas for NIH-wide Challenges and Opportunities
Notice Number:

Key Dates

Release Date:
Response Date:
August 11, 2023

Related Announcements


Issued by

Office of Strategic Coordination (Common Fund)


The purpose of this Request for Information (RFI) is to solicit ideas on NIH-wide challenges and opportunities that may be of interest to the NIH Common Fund.


The Common Fund supports bold scientific programs that catalyze discovery across all biomedical and behavioral research. These programs bring together investigators and multiple NIH Institutes and Centers (ICs) to collaborate on innovative research. Common Fund programs are expected to address high priority challenges for the NIH as a whole and make a broader impact in the scientific community. Many Common Fund programs are designed to produce specific deliverables, such as broadly useful datasets, tools, technologies, research methods, or fundamental scientific paradigms. These deliverables are expected to have exceptional impact on the way science is conducted, our understanding of human physiology or disease, or our ability to support human health.

Common Fund investments share the following characteristics:

  • Transformative – high potential to dramatically affect biomedical and/or behavioral research over the next decade
  • Catalytic – must achieve a defined set of high impact goals within a defined period of time
  • Synergistic – outcomes must synergistically promote and advance individual missions of NIH ICs to benefit health
  • Cross-cutting – programs must cut across missions of multiple ICs, be relevant to multiple diseases/conditions, and be sufficiently complex to require a coordinated, trans-NIH approach
  • Unique – must be something no other entity is likely or able to do

Information requested

The NIH requests ideas for biomedical and behavioral research challenges and opportunities that may be of interest to the Common Fund. These ideas may inform activities to advance areas of science relevant to these challenges/opportunities, including, but not limited to, scientific workshops, pilot initiatives, and/or future Common Fund programs.

NIH encourages idea submissions that may include, but are not limited to, the following:

  • A critical challenge or exciting emerging opportunity in biomedical/behavioral research
  • Resources, tools, or knowledge that are needed to address the important challenge or opportunity
  • Scientific advancements or other factors that make addressing the important challenge or opportunity particularly timely

Please consider:

  • The potential impact on human health
  • The work that could be accomplished in 5 to 10 years

NIH encourages concise ideas to facilitate the review process. Submissions should focus on broad concepts rather than detailed descriptions.

How to submit a response

All responses must be submitted electronically on the submission website.

Responses must be received by 11:59:59 pm (ET) on August 11, 2023.

Responses to this RFI are voluntary and may be submitted anonymously. Please do not include any information you do not wish to be made public. Proprietary, classified, confidential, or sensitive information should not be included in your response. The Government will use the information submitted in response to this RFI at its discretion. The Government reserves the right to use any submitted information on public websites, in reports, in summaries of the state of the science, in any possible resultant solicitations(s), grant(s), or cooperative agreement(s), or in the development of future funding opportunity announcements. This RFI is for information and planning purposes only and is not a solicitation for applications or an obligation on the part of the Government to provide support for any ideas identified in response to it. Please note that the Government will not pay for the preparation of any information submitted or for use of that information.


Please direct all inquiries to:

Stephanie Courchesne, Ph.D.
Office of the Director (OD)