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NOT-RM-11-005: Notice of Intent to Publish a Request for Applications for NIH-HMO Collaboratory Coordinating Center Limited Competition (U54)

Notice of Intent to Publish a Request for Applications for NIH-HMO Collaboratory Coordinating Center Limited Competition (U54)

Notice Number: NOT-RM-11-005

Key Dates

Release Date:  January 3, 2011

Issued by

National Institutes of Health (NIH)
Common Fund (Roadmap)


The National Institutes of Health Common Fund intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for development and implementation of a Coordinating Center (CCC) as part of the HMO Collaboratory. (See http://nihroadmap.nih.gov/hmocollaboratory/.)

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.  The eligibility to apply in response to this FOA is limited to members of the HMO Research Network (HMORN). This limited competition will allow consortium agreement(s) with non-HMORN members. Applicants are encouraged to partner with organizations with particular expertise in data integration.

The FOA is expected to be published in the winter of 2011 with an expected receipt date in the spring of 2011.

This FOA will utilize the U54 activity code. Details of the planned Funding Opportunity Announcement (FOA) are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insights into the area of distributed network infrastructure evaluation and development to begin to consider applying for this new FOA. Collaboratives combining expertise in informatics, electronic health records, biorepositories, biostatistics, mega-epidemiology, economics, decision analysis, ethics, pragmatic clinical trials, comparative effectiveness research, behavioral science, environmental health, and health policy will be encouraged and these investigators should also begin considering applying for this application.

The Collaboratory Coordinating Center is expected to significantly exceed the breadth, scope, and complexity of the previously funded limited infrastructure support of the HMO Research Network (HMORN). The long term goal of the NIH Common Fund Collaboratory project is to strengthen the capacity, capability and cost-effectiveness of large and/or multi-site studies by making use of primary clinical data and samples in a distributed network of integrated health care delivery organizations. The overall goals of the Collaboratory Coordinating Center may include: evaluating and advancing the governance, quality, use, depth and scale of electronic data and biospecimen collection, as well as operational infrastructure for clinical and health services delivery research. This infrastructure will ultimately serve researchers to efficiently generate new evidence on the effectiveness, or comparative effectiveness, of healthcare interventions. This work will substantially enhance the Nation’s capability and capacity to systematically collect and curate prospective and retrospective data that will inform research in populations typically under-represented in randomized controlled clinical trials, such as patients with multiple co-morbidities, extremes of age, rural populations, and minorities.



Please direct all inquiries to:

Laura Lee Johnson, Ph.D. on behalf of the HMO Collaboratory Working Group
6707 Democracy Blvd.
Suite 401, MSC 5475
Bethesda, MD 20892-5475 (For express/courier, use 20817)
Phone: 301-435-2591 Fax: 301-480-3621
Email: johnslau@mail.nih.gov
Website: http://commonfund.nih.gov/hmocollaboratory/

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
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and Human Services (HHS)
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