Request for Information (RFI): Soliciting Input on Current Needs in the NIH Roadmap Molecular Libraries and Imaging Initiative

Notice Number: NOT-RM-09-002

Key Dates
Release Date: October 29, 2008
Response Date: December 21, 2008

Issued by
This is a time-sensitive Request for Information (RFI) issued by the Molecular Libraries and Imaging Working Group ( of the NIH Roadmap for Medical Research. The information from this RFI will be collected by the NIH Office of Portfolio Analysis and Strategic Initiatives ( and shared with Working Group members from across the NIH, in order to ascertain the needs of the field.

Information Requested


We are requesting community input on challenges and barriers to the Molecular Libraries and Imaging initiative. The targeted items asked are intended to reveal gaps and highlight the opportunities, and to aid in identifying specific, achievable goals that will advance and transform the chemical genomics field. 

This RFI is for planning purposes only, and should not be construed as a solicitation for applications or proposals and/or as an obligation in any way on the part of the United States Federal Government. The Federal Government will not pay for the preparation of any information submitted and/or for the Government’s use of that information. All submitted information shall remain with the Federal Government and will not be returned.


NIH invites responses from the scientific community, scientific organizations, pharmaceutical companies, federal agencies, and other interested parties well-versed in the areas of chemical genomics, to help identify crucial needs, gaps and roadblocks to related research. Collectively, we want to identify ways in which NIH can effectively and efficiently address these barriers.

As you formulate responses, please consider that NIH is interested in replies that promote transformative ideas and approaches through concrete and achievable tasks. Moreover, NIH wants to leverage existing research mechanisms and resources. Ideas for enabling research efforts of interest would address those challenges for the Molecular Libraries Screening/Production Centers Network (MLSCN/MLPCN) and PubChem that: (1) are activities that no other entity is likely to be able to successfully conduct, (2) will generate knowledge that can be made publicly accessible, and (3) are of clear benefit to public health.

NIH wants to broadly advance the field, and in keeping with the missions of the individual institutes and the NIH and DHHS as a whole, to benefit and improve the health of the nation. The ultimate goal is to facilitate assay and probe development and enable the most rapid discovery possible.


Responses must be submitted electronically at, and will be accepted through December 21, 2008. Replies to any individual elements of the webform are optional, and the site will permit anonymous responses. The information provided will be analyzed and may appear in various reports. Additionally, the government cannot completely guarantee the confidentiality of the information provided.


Specific questions about this RFI should be directed to the contact listed below:

Scott W. Jackson
Process Manager
NIH Roadmap for Medical Research
Office of the Director, NIH
Office: 301-496-9123

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