Notice Announcing NIH All of Us Research Program Engagement, Communications, and Enrollment Partners Other Transactions (OT) Research Opportunity Announcement (ROA)
Notice Number:

Key Dates

Release Date:

July 14, 2022

Related Announcements

OTA-22-006 - NIH All of Us Engagement, Communications, and Enrollment Partners Other Transactions (OT) Research Opportunity Announcement (ROA)

Issued by

Office of The Director, National Institutes of Health (OD)


Research Opportunity Announcement (ROA) Title: All of Us Engagement, Communications, and Enrollment Partnerships

ROA Number: OTA-22-006

ROA Open Period: May 26, 2022 to May 23, 2025 (Note: open solicitation period includes multiple white paper deadlines within each calendar year)


The All of Us Research Program, within the Office of the Director (OD), has issued a research opportunity announcement (ROA) to solicit white papers supporting various Areas of Interest (AOIs). A ROA is a method of solicitation that announces the anticipated availability of Other Transactions (OT) awards, a special type of legal instrument other than contracts, grants, or cooperative agreements.


The All of Us Research Program is a historic effort to gather data from at least 1 million people, with the goal of accelerating health research and medical breakthroughs, and enabling individualized prevention, treatment, and care. The program is creating a national research resource to inform thousands of studies, covering a wide variety of health conditions. Researchers will use data from the program to learn more about how individual differences in lifestyle, environment, and biological makeup can influence health and disease.

The purpose of this announcement is to fund organizations who can help All of Us build its cohort of volunteers who reflect the rich diversity of the United States and are actively engaged as partners. These funded organizations will help design and implement strategies to raise awareness of the program through community and health care provider organizations, drive increased enrollment of participants, foster regular communication with participants, and engage the research community to use the data being gathered.

Award Project Duration: Award periods are anticipated to be up to five (5) years but may be shortened or extended as needed.

Pre-Submission Webinar: A webinar will be conducted for potential offerors. The purpose of the webinar will be to provide potential offerors with a better understanding of the scope of the All of Us Research Program and objectives of this ROA. The date and time of the webinar will be made available via the link below.

White Paper Deadlines: This ROA will remain open for three (3) years from its issue date, unless otherwise updated via an amendment on, and includes multiple white paper (WP) submission deadlines. All WP deadline times are 3:00 PM Eastern Time. The first white paper deadline is August 31, 2022. Additional deadlines, are listed in the full opportunity announcement on

Documents and Related Links: The full ROA package can be accessed via the following link: Potential offerors are encouraged to carefully review the announcement in its entirety before submitting questions and/or preparing a white paper submission.


Please direct all inquiries to:

All of Us Research Program

Awards Management Branch (AMB)

All of Us ROA Inquiries: