Update for RFA-OH-22-004 "World Trade Center Health Research related to WTC Survivors (U01-No Applications with Responders Accepted)"
Notice Number:

Key Dates

Release Date:

August 12, 2022

Related Announcements

RFA-OH-22-004 - World Trade Center Health Research related to WTC Survivors (U01-No Applications with Responders Accepted)

Issued by


Centers for Disease Control and Prevention (CDC)


The updated requirements, guidance, instructions, and other information for RFA-OH-22-004 are effective with the publication date of this notice.

Among many health conditions that may be explored, there are several conditions that have come to light as a result of concerns expressed by the affected population. These health conditions include, but are not limited to, endocrine-related disorders, including metabolic syndrome; reproductive health outcomes, such as polycystic ovary syndrome (PCOS), endometriosis, and infertility; autoimmune and neurodegenerative diseases; and cancer among individuals exposed to the WTC disaster at younger ages (18 years of age or younger).

In response to health equity initiatives, opportunities for future health effects research involving vulnerable groups of persons (e.g., minorities, women, children, and other potentially disadvantaged groups) who were exposed to the 9/11 attacks and aftermath are of special interest. Research is urgently needed to identify at-risk groups, characterize the health burden, and inform care. Potential projects include (but are not limited to) research targeted to:

  • Develop and apply methods for identifying a cohort of eligible young adult study subjects (exposed and control groups) and determine their willingness to participate in future health effects research. These methods include, but are not limited to, community-based approaches to recruitment that engage existing outreach and education partners and mixed methods research to assess health concerns and interests in research participation.
  • Develop methods to systematically determine whether there are unique vulnerabilities and health disparities in groups within the population of individuals exposed to the 9/11 attacks and its aftermath.

Length of the Award Project Period

Applications are now limited to a maximum project period of three years. NIOSH will consider the following types of U01 cooperative research projects for 2022 due date/FY2023 funding.

Type of Project

Project Period

Total Cost per Year


Up to three years

Up to $500K


Up to two years

Up to $350K

The Research Strategy component of the Research Plan is limited to 8 pages for intermediate-term (up to 3 years) or short-term (up to 2 years) projects. These page limits are the totals for all text, tables, graphs, figures, diagrams, and charts in this component.

Note to Applicants

You must include a Data Management Plan (DMP) in the Resource Sharing Plan(s) of the PHS 398 Research Plan Component of the application for each proposed collection of public health data. Additionally as noted, the following components are required for this FOA, and must be included as attachments in the "12. Other Attachments" section of the "R&R Other Project Information" section of the application. When uploading documentation into this application package, clearly label the documents for easy identification.

1. Project Dissemination Plan

2. Project Evaluation Plan

3. Study Information as an attachment that includes WTC Subpopulation(s) under study (WTC survivors; see Section I. Target Population for descriptions), Primary Diseases/Conditions, and the Study Design of your proposed study.

4. Risk Assessment Questionnaire (include form and supporting documentation)

5. Duplication of Efforts (required if this application will result in programmatic, budgetary, or commitment overlap with another application or award submitted to another funding source in the same fiscal year. Write "No Overlap" if no overlap.)

Section I. Funding Opportunity Description

Data Center and WTC Health Registry Contacts

Fire Department of New York

Medical Director – Dr. David Prezant, 718-999-2696, David.Prezant@fdny.nyc.gov

Administrative Director – Ms. Jessica Weakley, 718-999-0412, Jessica.Weakley@fdny.nyc.gov

Associate Director, WTC FDNY Data Center – Dr. Rachel Zeig-Owens, 718-403-4416, Rachel.Zeig-Owens@fdny.nyc.gov

Mount Sinai School of Medicine

Director – Dr. Andrew C. Todd, 212-824-7053, Andrew.Todd@mssm.edu

Data Requests – Mr. Christopher R. Dasaro, 332-323-2806, Christopher.Dasaro@mssm.edu

NYC Health and Hospitals Corporation

Medical Director – Dr. Joan Reibman, 212-263-6479, Joan.Reibman@nychhc.org

Executive Director – Ms. Angeles Pai, 212-788-3466, paia@nychhc.org

Data Center Director – Ms. Michelle Hyde, 212-788-0949, Michelle.Hyde@nychhc.org

WTC Health Registry

Paul Gambino, 718-786-4481, pgambino1@health.nyc.gov

Section III. Eligibility Information

PLEASE NOTE: Effective April 4, 2022, applicants must have a Unique Entity Identifier (UEI) at the time of application submission. The UEI replaced the Data Universal Numbering System (DUNS) and is generated as part of SAM.gov registration. Current SAM.gov registrants have already been assigned their UEI and can view it in SAM.gov and Grants.gov. Additional information is available on the GSA website, SAM.gov, and Grants.gov-Finding the UEI.

Section IV. Application and Submission Information

Applicants must use FORMS-G application packages.

Application guides for FORMS-G application packages are posted to the How to Apply - Application Guide page.


Please direct all inquiries to:

James Yiin, PhD
Scientific Program Official
National Institute for Occupational Safety and Health (NIOSH)
Centers for Disease Control and Prevention (CDC)
Telephone: 513-841-4271
Email: JYiin@cdc.gov