July 1, 2024
Office of The Director, National Institutes of Health (OD)
This Notice replaces NOT-OD-23-146 and provides program-specific information for the Extramural Clinical Research Loan Repayment Program for Individuals from Disadvantaged Backgrounds (LRP-IDB). The NIH Loan Repayment Programs (LRPs) are programs established by Congress and designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers. Additional detailed information about each LRP is provided at www.lrp.nih.gov.
The NIH invites qualified health professionals who contractually agree to engage in NIH mission-relevant research for an average of at least 20 hours each week for at least two years, initially, to apply for an award in the Extramural LRP. The Extramural LRP repays up to $50,000 annually of a researcher's qualified educational debt in return for a commitment to engage in NIH mission-relevant research at a domestic, nonprofit, or government entity. Research funding from NIH is not required to participate in the Extramural LRP. LRP awards are based on an applicant's potential to build and sustain a research career.
Extramural LRP applications will be accepted from September 1 until November 21, 2024. All LRP applications must be submitted electronically using the Application Submission System & Interface for Submission Tracking (ASSIST): https://public.era.nih.gov/assist/.
Expanded NIH Participation in LRP-IDB
As of September 1, 2023, NIH participation in the LRP-IDB was expanded to include all NIH Institutes and Centers (ICs). Previously, all LRP-IDB applications were assigned to and reviewed by the National Institute on Minority Health and Health Disparities (NIMHD). LRP-IDB applicants can now select one NIH IC from a drop-down list when applying. Applicants may also choose one additional IC for a secondary review assignment. Assignments are determined by the Division of Receipt and Referral, Center for Scientific Review. Although an applicant's selection will be taken under consideration, it is not a guarantee of a desired assignment.
Applicants are strongly encouraged to review each IC Mission and Research Priorities statement and then contact one or more IC scientific LRP liaisons to discuss their research and career interests as they relate to the research and funding priorities of the selected IC. Research and funding priorities can change on a yearly basis, thus it is imperative that applicants contact a liaison to ensure an appropriate understanding of IC priorities. A list of NIH IC scientific LRP liaisons is available on this web page: www.lrp.nih.gov/contact_us/contact_list.aspx.
LRP-IDB Objective
The objective of the LRP-IDB is to recruit and retain highly qualified health professionals from disadvantaged backgrounds into clinical research careers. The emphasis on clinical research and individuals from disadvantaged backgrounds highlights the need for the involvement of a cadre of competent health professionals in clinical research.
NIH defines Clinical Research as patient-oriented research conducted with human subjects, or research on the causes and consequences of disease in human populations involving material of human origin (such as tissue specimens and cognitive phenomena) for which an investigator or colleague directly interacts with human subjects in an outpatient or inpatient setting to clarify a problem in human physiology, pathophysiology or disease, or epidemiological or behavioral studies, outcomes or health services research, or developing new technologies, therapeutic interventions, or clinical trials.
An individual from a disadvantaged background is defined as an individual who comes from (1) an environment that inhibited the individual from obtaining the knowledge, skill, and ability required to enroll in and graduate from a health professions school; or (2) comes from a family with an annual income below a level based on low-income thresholds according to family size published by the U.S. Bureau of the Census, adjusted annually for changes in the Consumer Price Index, and adjusted by the Secretary of Health and Human Services for use in all health professions programs. The Secretary periodically publishes these income levels in the Federal Register. An applicant must demonstrate his/her disadvantaged background status under the above definition by submitting: (a) a written statement from the individual's former health professions school(s) that indicates that he/she qualified for Federal disadvantaged assistance during attendance; or (b) documentation that he/she received any of the following financial aid: Health Professions Student Loans (HPSL) or Loans for Disadvantaged Student Program; or (c) documentation that he/she received scholarships from the U.S. Department of Health and Human Services (DHHS) under the Scholarship for Individuals with Exceptional Financial Need.
Eligible Applicants
No applicant will be excluded from consideration on the basis of age, race, culture, religion, gender, sexual orientation, disability, or other non-merit factors.
Eligibility criteria to participate in the Extramural LRP:
The following individuals are ineligible for participation in the Extramural LRP:
Funds Available
The NIH intends to commit approximately $1 million annually to fund LRP-IDB awards.
Where to Obtain Additional Information: Please visit the LRP website at www.lrp.nih.gov, email lrp@nih.gov, or call the Division of Loan Repayment Information Center toll-free at (866) 849-4047. Applicants are strongly encouraged to pay attention to Institute or Center (IC) specific funding priorities, and discuss their career interests with an IC scientific liaison: www.lrp.nih.gov/contact-engage.
Application Receipt, Peer Review, and Review Schedule: Upon receipt, applications for both new and renewal awards will be reviewed for eligibility and completeness. Incomplete or ineligible applications will not be considered. Applications that are complete and eligible will be forwarded for peer review.
Application Materials:
The following information is furnished by applicants or others on behalf of applicants using ASSIST, https://public.era.nih.gov/assist/, and must be submitted from September 1 through November 21, 11:59 p.m. EST.
Applicants submit the following:
Research mentors submit the following:
Referees/Recommenders submit reference letters:
Information is obtained from individuals who can comment on the research skills and the abilities of the applicant. Reference letters are expected to include the following information about the applicant:
Institutional Business Officials submit a certification that:
Renewal Award Applications
Loan repayment awardees who wish to apply for a renewal award should do so no earlier than the year before their current award ends. LRP renewal awards are available for one- or two-year periods and are based on the same criteria used for new awards, plus two additional criteria: an assessment of research accomplishments and the applicants development as an independent investigator. A detailed description of research accomplishments during the most recent award period is required. Progress toward becoming an independent investigator is a major factor in granting a renewal award.
LRP policy allows a thirty-seven-month period (starting the day after the last day of the most recent LRP award) for submitting a renewal award application. After thirty-seven months, any submission will be considered a new award application, regardless of whether an unsuccessful application was submitted during the thirty-seven month period. Renewal awards are competitive, and submitting an application does not guarantee receiving a renewal award.
Change of Institution
A change of institution after the application submission deadline may be permissible, pending approval from the Institute or Center reviewing the application. All applicants must submit a Change of Institution (COI) request to the NIH Division of Loan Repayment immediately whenever there is a pending change in the applicant's employment, the scope of a submitted research plan, or research mentors. All COI applications must be submitted by January 31 for the application to be considered for review. A COI applicant must meet all LRP eligibility criteria, and COI requests are subject to final approval by the NIH Institute or Center reviewing the application. Approval of COIs is not guaranteed. Notification of a COI after the January 31 deadline will result in the application being withdrawn from funding consideration.
Post-submission Application Materials
Applicants may submit certain types of application materials after the application submission deadline if they result from unforeseen administrative issues or events. These materials must be received by the Division of Loan Repayment via email at lrp@nih.gov by January 31. Allowable post-submission materials for LRP applications are:
No modifications will be made to the original application. Any post-submission materials will be shared with reviewers as a separate addendum. To ensure fairness, no post-submission materials will be accepted after January 31. Additionally, there are no guarantees that any updated information will be included for review.
Evaluation Criteria
Applications for the Extramural LRP are evaluated against the following criteria as related to the likelihood that the applicant will continue in a career focused on research in one of the following program areas:
Applicant's potential to pursue a career in research, including:
Quality of the overall environment to prepare the applicant for a research career, including:
For renewal award applications, progress under the previous project period is an additional evaluation criterion:
Program Administration Details
Under the LRP, the NIH will repay a portion of the extant qualified educational loan debt incurred to pay for the researcher's undergraduate, graduate, and/or health professional school educational expenses. It is the LRP awardees responsibility to notify the Division of Loan Repayment immediately if there is a pending change in employment, research focus, or extended leave. Failure to fulfill the terms of the LRP contract will result in termination of the LRP award and could be considered a breach of contract. The penalty for a breach of contract is $7,500 for every month of unfulfilled service or $31,000, whichever is higher.
LRP service obligation and NRSA service payback cannot overlap, and deferral of NRSA payback is automatic upon acceptance of an LRP award.
The NIH will repay lenders for the extant principal, interest, and related expenses (such as the required insurance premiums on the unpaid balances of some loans) of educational loans from a U.S. government entity, academic institution, or a commercial or other chartered U.S. lending institution, such as banks, credit unions, savings and loan associations, not-for-profit organizations, insurance companies, and other financial or credit institutions which are subject to examination and supervision in their capacity as lending institutions by an agency of the United States or of the State in which the lender has its principal place of business, obtained by applicants for the following:
Loan repayments are made directly to lenders, following receipt of (1) the Research Supervisor's verification of completion of the prior period of research, and (2) lender verification of the crediting of prior loan repayments, including the resulting account balances. The NIH will repay loans in the following order:
1. Loans guaranteed by the U.S. Department of Health and Human Services:
2. Loans guaranteed by the U.S. Department of Education:
3. Loans made or guaranteed by a State, the District of Columbia, the Commonwealth of Puerto Rico, or a territory or possession of the United States
4. Loans made by academic institutions
5. Private (Alternative) Educational Loans:
The following loans are NOT repayable under this program:
1. Loans not obtained from a U.S. or other government entity, academic institution, or a commercial or other chartered U.S. lending institution such as loans from friends, relatives, or other individuals, and non-educational loans (e.g., home equity loans)
2. Loans for which eligibility documentation (current account statement, and promissory note or lender disclosure statement) is not provided
3. Consolidation loans that include a loan not eligible for repayment, such as loans obtained from an unqualified lender, loans obtained by the applicant for an individual other than the applicant (e.g., spouse or child), loans obtained by an individual other than the applicant (e.g., spouse or parent), or non-educational loans (e.g., home equity loan)
4. Loans or portions of loans obtained for educational or living expenses that exceed a reasonable level as determined by the standard school budget for the year in which the loan was made
5. Loans, financial debts, or service obligations incurred under a program where an incurred service obligation converts to a loan upon failure to satisfy the service obligation
6. Loans that are delinquent, in default, or not current in their payment schedule
7. Parent PLUS loans
8. Loans that are paid-in-full
9. Loans obtained after the start date of the first NIH LRP award (e.g., a promissory note signed after the start date of an LRP award). This provision does not apply to qualifying loan consolidations.
Before the commencement of loan repayment, or during lapses in loan repayments, due to administrative complications, Leave Without Pay (LWOP), or a break in service, LRP awardees are wholly responsible for making payments or other arrangements that maintain loans current, such that increases in either principal or interest do not occur. Penalties and/or fees assessed to awardees failing to maintain their current payment status may not be considered for reimbursement.
LRP payments are NOT retroactive. Loan repayment will commence after a loan repayment award begins, expected to be no earlier than July 1 and no later than September 30 annually.
Required Federal Citations
Awards are made pursuant to Section 2022 of the 21st Century Cures Act (Public Law 114-255), which amended Section 487B of the Public Health Service Act (42 U.S.C. 288-2) to consolidate all NIH Extramural Loan Repayment Programs into a single Extramural Loan Repayment Program while retaining Clinical Research for Individuals from Disadvantaged Backgrounds as a subcategory.
Please direct all inquiries to:
Additional detailed information about the NIH Loan Repayment Programs is provided at https://www.lrp.nih.gov/eligibility-programs. Applicants are strongly encouraged to discuss their career interests with an NIH Institute or Center scientific liaison provided at this site: https://www.lrp.nih.gov/contact-engage.