NIH Guidance on Marking Changes in Resubmission Applications
Notice Number:

Key Dates

Release Date:

February 13, 2024

Related Announcements

  •  December 4, 2014 - NIH Modification to Guidance on Marking Changes in Resubmission Applications. See Notice NOT-OD-15-030. (RESCINDED)

Issued by



This Notice informs the applicant community that, effective May 25, 2024, this guidance replaces previous guidance on marking changes in Resubmission applications. The use of markups such as bracketing, indenting, highlighting, bolding, italicizing, underlining, margin lines, change in typography, font, or font color, or any other type of markup should not be used to identify changes in Resubmission applications.

Changes made to a Resubmission application should only be outlined in the Introduction attachment. The Introduction must include a summary of substantial additions, deletions, and changes to the application. It must also include a response to weaknesses raised in the Summary Statement. Unless otherwise indicated in the Table of Page Limits, the Introduction may not exceed one page.


Please direct all inquiries to:

NIH Review Policy Officer

Office of Extramural Activities (OER)

For more information, please see the Resubmission Frequently Asked Questions page.

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices