EXPIRED
November 17, 2022
NOT-OD-22-026 - Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional)
PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Office of The Director, National Institutes of Health (OD)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
National Human Genome Research Institute (NHGRI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Nursing Research (NINR)
National Institute on Minority Health and Health Disparities (NIMHD)
National Library of Medicine (NLM)
Fogarty International Center (FIC)
National Center for Complementary and Integrative Health (NCCIH)
National Center for Advancing Translational Sciences (NCATS)
National Cancer Institute (NCI)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Office of Research on Women's Health (ORWH)
Office of Data Science Strategy (ODSS)
Sexual and Gender Minority Research Office (SGMRO)
Tribal Health Research Office (THRO)
The NIH Office of Science Policy (OSP) within the Office of the Director (OD) announces the availability of administrative supplements to support 1) research on bioethical issues to develop or support the development of an evidence base that may inform future policy directions, and/or 2) certain efforts to develop or augment bioethics research capacity. Applicants may propose to supplement parent awards focused on bioethics or to address a component related to bioethics in a biomedical and/or health-related behavioral research study. Note that applications must be within the general scope of the parent award.
Background
Ethical considerations are intrinsic to the conduct of biomedical and health-related behavioral research and the translation of scientific and technological advances into practice. Research into bioethical issues can provide an evidentiary basis to guide conduct, content, and/or application of the biomedical and health-related behavioral sciences and their associated policies, which becomes of increasing importance as science and societal views continue to evolve. Ethical questions and challenges are interlinked with many of NIH’s general areas of scientific priority, such as responding to public health needs (e.g., COVID-19, the opioid crisis, desire for precision medicine interventions) and emerging scientific opportunities (e.g., new data sharing infrastructure, innovative technologies). The investment in and the integration of bioethics-related research and policy demonstrate NIH’s commitment to advancing the most ethical research possible, which, in turn, can facilitate public participation and trust in the research enterprise.
Specific Areas of Interest
OD is particularly interested in applications that identify, analyze, and/or address bioethical issues related to digital health and/or real-world data; participant engagement; return of research results for individuals, families, communities, and/or society; and data sharing. Examples of such projects include, but are not limited to:
Digital Health and/or Real-World Data
Designing and evaluating tools or approaches to aid individual, family, and community decision-making about use of digital health technologies and/or real-world data
Studies that examine understanding of ethical issues related to digital health and/or real-world data among researchers and/or examine issues related to disclosure of information about the use of digital health and/or real-world data for biomedical and/or health-related behavioral research
Evaluations of practices related to using digital health technologies in research, including issues related to data privacy and data security, consent, transparency, access, and equity
Analyzing ethical, legal, and policy issues raised by use of digital health technologies in research
Considerations for using digital health data and/or real-world data to generate knowledge for biomedical and/or health-related behavioral research
Participant Engagement
Studies on participant and community engagement or participatory research methods, including participant voices in clinical trial design and outcomes and longer-term engagement with the scientific enterprise
Participant attitudes on the collection and use of longitudinal, multidimensional data from disparate sources, including data privacy and data security considerations
Return of Research Results
Assessments of participant preferences regarding the return of individual research results and methods for returning various types of research results to participants across various clinical fields, including results from clinical tests, environmental health measurements, and non-genomic data
Research to help understand how people make sense of and act upon individual research results
Data Sharing
OD also seeks to fund research on additional bioethics topics. Applications should propose 1) research on topics that can develop or support the development of an evidence base that may inform future policy directions, and/or 2) projects that support certain efforts to develop or augment bioethics research capacity.
Research on topics that can develop or support the development of an evidence base that may inform future policy directions
Policies of interest include current NIH-issued policies or potential future policy directions, other federal policies, laws, and regulations, as well as policies governing the practice of research, medicine, or public health. Issues of interest should fall within the scope of research supported by the NIH but may be beyond the focus of any one Institute or Center. Overarching areas of interest may include but are not limited to:
New and emerging technology development and use (e.g., gene editing, organoids, artificial intelligence, machine learning, neural implants and invasive or non-invasive modulation, consumer-generated data, synthetic biology)
Big data and data science analytics, integration of data for research (e.g., clinical, research, environment, social media, participant/patient provided, other data types), biases in datasets and algorithms, research using electronic health record data, and ethical implications for the use of non-traditional data (e.g., social media information, consumer data) for research purposes
Precision and personalized medicine
Personal, institutional, and research privacy and security
Learning Healthcare System, interface of clinical research and clinical care, and pragmatic trials
Crowdsourcing, citizen science, and DIY biomedical and/or health-related behavioral research
Participant driven, directed, or sponsored clinical research
Issues related to public health research, including emergency, disaster, and pandemic research
Individual or community health, treatment, and/or research disparities; accessing and sharing benefits of research; post-study obligations; patient access to drugs and medical services
Issues related to the inclusion of populations underrepresented in biomedical and/or health-related behavioral research, including sexual and gender minorities, people from racial and ethnic minority groups, people living with disabilities, non-U.S. born persons, people experiencing poverty, older adults, formerly or currently incarcerated individuals, and other marginalized communities
Issues related to the inclusion of Tribal members and American Indian/Alaska Native populations in biomedical and/or health-related behavioral research
Research involving individuals who are pregnant/lactating
Research involving individuals potentially at higher risk for undue influence, including for pediatric and palliative care research
Issues related to aging research
Issues related to health disparities and health inequities, including effects of structural racism on the biomedical and health-related behavioral research enterprise
Current and emerging regulatory and policy environments, including NIH environments
Innovative study design, conduct, management, and oversight, including methods for obtaining and documenting informed consent, virtual clinical trials, and other remote or passive sensing, monitoring or assessment methods
International research, including research in resource-constrained settings, transnational research, and research in low- and middle- income countries
Research on stigmatized conditions
Historical analyses of bioethics issues
Novel approaches for developing, enhancing, and measuring effectiveness of bioethics infrastructure and training
New means for assessing and enhancing the scientific workforce, including policies promoting scientific workforce diversity and inclusion and promoting a safe and inclusive research environment
Issues related to collecting, analyzing, and applying data related to social determinants of health
Projects that support certain efforts to develop or augment bioethics research capacity
OD is interested in supporting capacity building projects that directly strengthen and/or sustain the field of bioethics. Capacity building efforts of particular interest may include the development of educational content (e.g., curricula, practicum experiences for trainees, publicly accessible web-based modules) and new or innovative resources, tools, and/or strategies addressing bioethical challenges. Other types of projects (e.g., IRB management, funding for employees to meet human subjects research competency requirements, training slots) will not be supported by this funding mechanism.
This announcement is intended to support projects that have a strong focus on bioethics. Investigators proposing capacity building projects should ensure that bioethics is the primary focus of the content/resource/tool/strategy being developed. The contribution of the proposed project to the field of bioethics should be made clear in the application.
IC areas of interest
In addition to overarching areas of interest, individual NIH Institutes, Centers, and Offices have indicated the following specific areas of research interest:
FIC
The Fogarty International Center (FIC) is interested in research and sustainable capacity building activities on ethical issues relevant to low- and middle-income countries, in particular studies conducted by investigators in these countries.
NCATS
The National Center for Advancing Translational Sciences (NCATS) is interested in research on ethical issues that cross disease domains and span the translational research spectrum. NCATS encourages collaboration between translational researchers and bioethics researchers on projects addressing ethical challenges in moving discoveries from laboratory, clinic, and community into interventions that improve health.
Note concerning the Award Project Period: Supplement project and budget periods are limited to the remaining active budget period that started in FY23 for the existing parent award. To be eligible, the parent award must be active (i.e., not be in an extension period), and the activities proposed in the supplement must be accomplished within the remaining active budget period that started in FY23 for the existing parent award. The earliest anticipated start date is July 1, 2023.
NCCIH
The National Center for Complementary and Integrative Health (NCCIH) is interested in bioethics applications that address topics relevant to its mission and research priorities as provided in its Strategic Plan.
For information, please see: https://nccih.nih.gov/about/plans.
NCI
The National Cancer Institute (NCI) is interested in bioethics issues relevant to cancer research and healthcare delivery, such as issues raised in cancer clinical trials, cohort studies, cancer prevention studies, cancer centers, cancer surveillance, prospective biobanking, studies using previously collected samples/tissues, or studies re-using previously collected data. Bioethical issues of interest include, but are not limited to:
Issues raised by novel cancer therapies or diagnostic technologies
Issues raised by use of genetic testing for cancer screening or prevention studies
Issues raised by use of ancestry markers vs. ethnicity/race in cancer research, care, or prevention
Issues raised by use of artificial intelligence or machine learning in cancer research or care
Issues raised by use of digital health technology (e.g., telehealth, wearables, implantable sensors, mobile apps in cancer research), including disparities in access to technology, inclusivity and usability of technology, and data ownership; see also the issues highlighted above on the impact of digital health and/or real-world data issues
Issues raised by use of social media as data sources or cancer control intervention platforms, including consent, privacy, data access, and algorithmic issues related to social media data
Privacy, confidentiality, and governance of data and ethical re-use of data, including data originally collected in a broad range of settings
Innovative models for data governance
Community, patient, or participant engagement
Return of research results
Participant or patient perception and comprehension
Effective communication and cancer prevention
Patient-centered communication, including patient-provider and to/within families
Prognosis and goals of care communication
Innovative methods and technologies for recruitment, retention, and ongoing engagement of participants who are underserved and/or vulnerable, hard to reach, or otherwise underrepresented in research
Access to care for populations with cancer disparities
Effective approaches to increase transparency in research
Issues related to cancer research on individuals whose age, illness, or cognitive impairment do not allow them to provide informed consent or independently complete self-report measures
Issues raised by advance care planning
Addressing challenges of conducting cancer-related trials on cannabinoids due to variations in state laws and access
NCI encourages investigators to contact the parent grant program officer to address any budgetary issues prior to submitting a supplement application.
NIAID
The National Institute of Allery and Infectious Diseases (NIAID) is interested in supporting supplemental projects that focus on ethical, legal, and social implications relevant to domestic and international collaborative research on HIV/AIDS or its co-morbidities (e.g., TB, malaria, hepatitis, sexually transmitted infections); other infectious diseases including those transmitted by vectors, immunologic and allergic diseases, and/or organ transplantation; ethics of clinical trials and implementation science; and other ELSI issues relevant to NIAID's scientific mission. Applications may include conceptual work in bioethics, or empirical work gathering and analyzing data relevant to ethical issues in research, or a combination of the two. For empirical projects, data collection may include quantitative or qualitative methods, or both. Although not intended to be an exhaustive list, of particular interest to the respective divisions of NIAID are projects on:
Research involving adolescents and young adults, including autonomy and informed consent
Policy issues at the intersections of public health surveillance, care delivery, and research
Issues within NIAID’s mission that are unique to child-bearing age and pregnant people
Enhanced engagement of key populations in research on HIV prevention, treatment, cure; HIV-related comorbidities and co-infections including those transmitted via sexual contact; improving dissemination, communication of results, mitigating barriers to research participation
Representation of key populations in research on immune-mediated diseases and transplantation for disease prevention, treatment, and/or cure; improving dissemination, communication of results, and mitigating barriers
Community engagement and attitudes concerning novel vector control measures, vaccines, other mitigation strategies for infectious diseases, and organ transplantation, including xenotransplants
Informing study designs for safety and efficacy evaluations of interventions, best practices for development and uptake of future therapeutics and/or prevention strategies
Best methods for securing highly sensitive data, including genetic data; risks from data breaches and reidentification; effective tools for anonymizing sensitive data; stakeholders attitudes toward data sharing methods and policies
Research on genome editing for correcting heritable traits and genetic disorders
NIBIB
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) is interested in bioethics research relevant to its mission to support the development of innovative technologies in bioimaging and bioengineering. Areas of particular interest to NIBIB include, but are not limited to, ethical issues related to:
Investigators are strongly encouraged to contact NIBIB staff to discuss their ideas. For more information on areas of interest to NIBIB, please visit: https://www.nibib.nih.gov/research-funding.
NIDA
The mission of the National Institute on Drug Abuse (NIDA) is to advance the science of drug use and addiction and to apply that knowledge to improve individual and public health through:
Strategically supporting and conducting basic, clinical, and epidemiological research on drug use, its consequences, and the underlying neurobiological, behavioral, and social mechanisms involved
Ensuring the effective translation, implementation, and dissemination of scientific research findings to improve the prevention and treatment of substance use disorders (SUDs), reduce the harms associated with drug use, guide policies, enhance public awareness of addiction as a chronic but treatable medical illness, and reduce stigma
NIDA’s research advances fundamental knowledge and provides scientific evidence to inform individual and public health, including the policies and practices of other federal agencies; state and local health, education, and human services; and the legal system.
NIDA is interested in bioethical issues relevant to research involving all individuals, with particular attention to individuals who have, or are at risk of developing, SUDs with particular emphasis on vulnerable populations, including children, adolescents, pregnant women, and those with other mental illnesses. Areas of particular interest in the context of this Bioethics NOSI include:
Identifying and developing approaches to reduce stigma
Understanding sex, sexual orientation, and gender differences
Identifying and developing approaches to reduce health disparities
Understanding interactions between substance use, HIV, and other comorbidities
Leveraging data science and analytics to understand real-world complexity
Developing personalized interventions informed by people with lived experience
NIDCR
The mission of the National Institute of Dental and Craniofacial Research (NIDCR) is to advance fundamental knowledge about dental, oral, and craniofacial (DOC) health and disease and translate these findings into prevention, early detection, and treatment strategies that improve overall health for all individuals and communities across the lifespan (see: https://www.nidcr.nih.gov/about-us/strategic-plan). In addition to the overarching priority areas of this notice as related to its mission, NIDCR is also interested in:
Management of incidental findings about overall health from studies that focus on DOC phenotypes using research, health, and clinical data collected under the same studies or elsewhere and crowd-sourced data
Privacy, confidentiality, inclusion, and bias related to the collection, analysis, and dissemination of research and clinical data, as well as re-use of data for different research questions, including facial images, audio and video samples, genetic variants, multi-omics, other deep phenotyping data, and associated metadata collected prenatally, postnatally, and through adulthood
Ethical and societal implications of screening or treatment approaches where risk calculations are especially relevant (e.g., applying regenerative medicine technologies to treating non-life-threatening DOC diseases and conditions, routine screening for health conditions in the dental setting)
Ethical and societal implications of applying precision medicine approaches to diagnosis, treatment, or management of DOC diseases and conditions
NIDDK
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is interested in applications that address topics relevant to its core mission.
For more information, please see: https://www.niddk.nih.gov/about-niddk/research-areas.
NIEHS
The mission of the National Institute of Environmental Health Sciences (NIEHS) is to discover how the environment affects people in order to promote healthier lives. NIEHS is interested in applications that advance the bioethics evidence base and/or support bioethics research capacity building and are within the scope of its 2018-2023 Strategic Plan (https://www.niehs.nih.gov/about/strategicplan/index.cfm). Specific areas of interest to NIEHS include, but are not limited to:
Bioethics Evidence Base:
Bioethics Research Capacity Building:
NINDS
The National Institute of Neurological Disorders and Stroke (NINDS) is interested in research on neuroethical questions relevant to its mission to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. In addition to the general areas of interest listed above, areas of interest specific to NINDS include, but are not limited to, the ethical implications of:
Consistent with the description of capacity building efforts above, NINDS also is interested in capacity building efforts, including the development of educational content and new or innovative resources, tools, and/or strategies addressing neuroethical challenges relevant to the NINDS mission.
NINDS, as part of NIH, strives for rigor and transparency in all research it funds. For this reason, NINDS explicitly emphasizes the NIH application instructions related to rigor and transparency (https://grants.nih.gov/policy/reproducibility/guidance.htm) and provides additional guidance to the scientific community (https://www.ninds.nih.gov/Funding/grant_policy).
Additional information about the NINDS mission may be found here: https://www.ninds.nih.gov/About-NINDS/Who-We-Are/Mission. Note that applications must consider neuroethical questions and be within the general scope of the parent award. Also, NINDS will not consider supplement applications that propose new basic research activities or research with vertebrate animals.
NEI
The National Eye Institute (NEI) is interested in bioethics applications that address topics relevant to research on mechanisms of visual function, prevention and treatment of vision diseases, and improving quality of life through expanding opportunities for people who are blind or have low vision.
NHGRI
The National Human Genome Research Institute (NHGRI) is interested in research related to the ethical, legal, regulatory, policy, economic, cultural and societal issues raised by the advancement and use of genomics, including, in combination with other omic data. These issues may relate to:
The design and conduct of research in genetics and genomics
The translation of genetic and genomic research into clinical medicine and health care
The interplay among a broad array of stakeholders in the field of genomics
The value and meaning of genomics for the broader public
Examples of possible topics of interest are available on the ELSI Research Areas and Sample Topics website: https://www.genome.gov/Funded-Programs-Projects/ELSI-Research-Program/research-areas.
NHLBI
The National Heart, Lung, and Blood Institute (NHLBI) is interested in research on bioethics issues relevant to its Strategic Vision (https://www.nhlbi.nih.gov/about/strategic-vision), and its focus on heart, lung, blood, and sleep conditions. Specific examples include, but are not limited to:
Addressing bias and health equity in heart, lung, blood, and sleep research
The return of research results (e.g., genomic, omic, environmental) with context to participants and communities, such as environmental toxins that may impact community health, the handoff between research and clinical care, and providing genetic counseling at large scales
Bioethical questions related to gene editing, such as examining the ethical issues of generating chimeric animals for human organ transplantation, discerning the difference between genetic therapy and genetic enhancement, consideration of the effect of patenting gene editing technologies, and consideration of the high cost of gene therapy and its effect on accessibility
Bioethical questions raised by the COVID-19 pandemic, such as ethical rationing of/equitable access to mechanical ventilators
Issues related to clinical trials, including adaptive clinical trial designs, usual care arms, or other novel designs
Bioethical questions related to implementation science research
Waivers of informed consent, exceptions from informed consent, or obtaining consent from surrogates
Ethics of cardiopulmonary support, including end-of-life care and support/device withdrawal
Novel and emerging technologies, such as machine learning bias or algorithm overreach and physician autonomy
Privacy and confidentiality, especially in large datasets, such as artificial intelligence applied to imaging data or concerns that may arise from multi-omics profiles
The impact of NIH policy changes, such as updates to the management of genomic summary results
Issues related to working with understudied or vulnerable populations or creating culturally appropriate messaging, especially with regards to American Indian/Alaska Native populations and Tribal Sovereignty
Investigators are encouraged to contact NHLBI staff to discuss their ideas.
NIA
The National Institute on Aging (NIA) is interested in applications that address topics relevant to its core mission. For more information, please see: https://www.nia.nih.gov/about/mission.
NIAAA
The mission of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) is to generate and disseminate fundamental knowledge about the effects of alcohol on health and well-being, and apply that knowledge to improve diagnosis, prevention, and treatment of alcohol-related problems, including alcohol use disorder (AUD), across the lifespan. NIAAA is interested in bioethics applications that address topics relevant to its mission, research objectives, and cross-cutting research areas as outlined in its Strategic Plan at: https://www.niaaa.nih.gov/strategic-plan.
Examples of bioethical issues of interest include but are not limited to:
Impact of stigma on recruitment and retention of clinical trial participants with alcohol misuse, AUD, and co-occurring disorders, including individuals from underserved, high-risk and hard to reach populations
Pharmacotherapy research involving pregnant people and adolescents
Issues related to the inclusion of females, sexual and gender minorities, and other populations underrepresented in alcohol research
Health provider attitudes towards patients with AUD in need of liver transplantation
Investigators are strongly encouraged to contact NIAAA staff to discuss their ideas
NIAMS
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is interested in bioethics applications that address topics of relevance to the NIAMS mission and research priorities as provided in its Strategic Plan: https://www.niams.nih.gov/sites/default/files/pdf/NIAMS-StrategicPlan-2020-2024-v1.pdf.
NICHD
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is interested in bioethical issues relevant to research involving children, pregnant people, and people with disabilities. Areas of particular interest include:
Research in the fields of developmental biology, reproductive health, pediatrics, population health, and medical rehabilitation
Research that addresses health disparities and improves prevention efforts among the populations served by NICHD
Areas identified as high-priority research areas to the institute are of particular interest
See https://www.nichd.nih.gov/grants-contracts/research-areas/priorities for the current research priorities for the institute and https://www.nichd.nih.gov/about/org/strategicplan regarding future themes for the Institute.
NIDCD
The National Institute on Deafness and Other Communications Disorders (NIDCD) is interested in applications that address topics in the areas of hearing, balance, taste, smell, voice, speech, and language. For more information, please see: https://www.nidcd.nih.gov/about/strategic-plans.
NLM
The National Library of Medicine (NLM) supports research that incorporates innovative biomedical informatics and data science approaches that harness the digital healthcare ecosystem and have the potential to reduce bias while improving personal health, access to care, continuity of care, and/or health outcomes. NLM’s vision is to unleash the potential of data and information to accelerate and transform discovery and improve health and health care. This important task understands that the use of data science and informatics methods, especially in health disparity populations, ethical principles of justice, benevolence, and respect must be maintained using health-related data. For more information about NLM, please see the Strategic Plan: https://www.nlm.nih.gov/pubs/plan/lrp17/NLM_StrategicReport2017_2027.pdf.
NLM’s interests include, but are not limited to, areas of science that address:
NIMH
The National Institute of Mental Health (NIMH) is interested in bioethics applications that address a range of issues for individuals and communities relevant to its core mission, and the subjects and disorders for which it serves as a primary lead at the NIH. Such areas include, but are not limited to:
Developing strategies to better engage participants, families, and other relevant groups in the research process as partners, not just subjects
How researchers can address changes in consent capacity among vulnerable research populations (e.g., children, cognitively impaired elders, actively psychotic patients)
Considering unique concerns and strategies to be applied in the thoughtful engagement of marginalized populations in biomedical research, while advancing understanding on how to avoid or mitigate against stigmatization, group harms, and unintended negative social implications/exacerbations of structural inequalities when conducting psychiatric research
Developing best practices and guidelines for sharing with patients clinically valuable and or medically actionable genetic results from psychiatric research, and implementation of the best practices in real world clinical settings (e.g., genetic counselling, stratifying patients, genetic diagnosis)
What are the issues/protections against bias, especially as related to racial, ethnic, or other underserved populations, that need to be considered when using novel data analytic approaches such as artificial intelligence, machine learning, or complex algorithms to inform clinical decision making
As data sharing in mental health research becomes more ubiquitous, what steps are necessary to protect participant privacy, data security, the appropriate use of data, and guard against the inappropriate use of data and unintended consequences of data sharing
Studies examining the bioethical issues related to suicide research that consider, but need not be limited to:
Suicide research in younger children (<10 years), including developmentally appropriate measures of suicidal intent, safe approaches to assessing suicide risk in young children, and developmentally appropriate interventions that mitigate risk for children endorsing suicidal thoughts or behaviors
Applications of various technologies for identifying suicide risk (e.g., risk algorithms, passive monitoring via worn sensors or web search behaviors, virtual reality paradigms), and approaches for monitoring and addressing states (real time, asynchronous, periodic review)
With input from research participants and families, developing best practices in suicide research for ethical consent of children and adolescents and parents/guardians, considering the research contexts where assent, consent, and combined consent/assent might be used, taking into account the study population, research questions and research design, participant burden, and ethical principles
These and additional suicide research bioethical issues identified in this document: https://www.nimh.nih.gov/funding/clinical-research/conducting-research-with-participants-at-elevated-risk-for-suicide-considerations-for-researchers.shtml
For further information about Institute priorities, please see: https://www.nimh.nih.gov/about/strategic-planning-reports/index.shtml.
NIMHD
The National Institute on Minority Health and Health Disparities (NIMHD) is interested in supporting research projects on the ethical, legal, and social implications of research participation and/or health care for racial/ethnic minority or other health disparity populations. Areas of interest to NIMHD include, but are not limited to:
NINR
The National Institute of Nursing Research (NINR) supports research to solve pressing health challenges and inform practice and policy - optimizing health and advancing health equity into the future. NINR discovers solutions to health challenges through the lenses of health equity, social determinants of health, population and community health, prevention and health promotion, and systems and models of care. Drawing on the strengths of nursing’s holistic, contextualized perspective, core values, and broad reach, NINR funds multilevel and cross-sectoral research that examines the factors that impact health across the many settings in which nurses practice, including homes, schools, workplaces, clinics, justice settings, and the community. Observational, intervention, and implementation research are of interest.
SGMRO
The Sexual & Gender Minority Research Office (SGMRO) is interested in bioethics applications that address topics relevant to NIH’s mission and research priorities provided in the NIH Strategic Plan to Advance Research on the Health and Well-being of Sexual and Gender Minorities FY 2021 2025.
For more information, please see: https://dpcpsi.nih.gov/sites/default/files/SGMStrategicPlan_2021_2025.pdf.
ORWH
The Office of Research on Women’s Health (ORWH) focuses on research that is relevant to the health of women, the inclusion of women in clinical studies, and the advancement of women in biomedical careers. ORWH is interested in research on bioethics issues that intersect with the goals, objectives, and guiding principles of the 2019-2023 Trans-NIH Strategic Plan for Women’s Health Research (https://orwh.od.nih.gov/about/trans-nih-strategic-plan-womens-health-research). Specific examples include, but are not limited to:
THRO
The Tribal Health Research Office (THRO) is interested in bioethics applications that address topics relevant to the goals and priorities outlined in the NIH Strategic Plan for Tribal Health Research FY 2019 - 2023.
For more information, please see: https://dpcpsi.nih.gov/sites/default/files/2019_THRO_StrategicPlan_508.pdf.
ODSS
The Office of Data Science Strategy (ODSS) is interested in stimulating research to identify, analyze, and understand relevant ethical issues and their implications in data science related to the F.A.I.R. (Findable, Accessible, Interoperable, and Reusable) and C.A.R.E. (Collective Benefit, Authority to Control, Responsibility, and Ethics) principles, data ecosystems, and data access and sharing, or policy development and implementation. For example, supporting projects that address 1) understanding ethical issues in broad knowledge domains to ensure ethical, meaningful, interpretable, and scalable utility of data from individuals and communities in individual, community, and population-level health and/or biomedical discovery and 2) enabling the expansion of diversity, equity, inclusion, and accessibility to enhance the scientific workforce for responsible data utility, access, and sharing.
Scope of Support
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Application and Submission Information
Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.
All instructions in the SF424 (R&R) Application Guide and PA-20-272 must be followed, with the following additions:
Scientific/Research Contact(s)
Shari Feirman, PhD
Office of Science Policy, Office of the Director (OSP/OD)
Telephone: 301-435-6350
Email: shari.feirman@nih.gov
Barbara Sina, PhD
Fogarty International Center (FIC)
Telephone: 301-402-9467
Email: sinab@mail.nih.gov
Elaine Collier, MD
National Center for Advancing Translational Science (NCATS)
Telephone: 301-435-0794
Email: colliere@mail.nih.gov
Wendy Weber, ND, PhD, MPH
National Center for Complementary and Integrative Health (NCCIH)
Telephone: 301-402-1272
Email: weberwj@mail.nih.gov
Charlisse Caga-anan, JD
National Cancer Institute (NCI)
Telephone: 240-376-6738
Email:charlisse.caga-anan@nih.gov
Cheri Wiggs, PhD
National Eye Institute (NEI)
Telephone: 301 402-0276
Email: wiggsc@mail.nih.gov
Nicole Lockhart, PhD
National Human Genome Research Institute (NHGRI)
Telephone: 301-385-1622
Email: lockhani@mail.nih.gov
Kathleen N. Fenton, MD, MS
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: 301-827-6523
Email: kathleen.fenton@nih.gov
Kristina McLinden, PhD
National Institute on Aging (NIA)
Telephone: 301-827-2563
Email: mclindenka@nih.gov
Pamela Wernett, PhD
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Telephone: 301-827-5391
Email: wernettpj@mail.nih.gov
Joana Roe
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-627-3213
Email:joana.roe@nih.gov
Emily Carifi, PhD
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Telephone: 301-496-0665
Email:emily.carifi@nih.gov
Tuba Fehr, PhD
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Telephone: 301-451-7958
Email: tuba.fehr@nih.gov
Tammara Jenkins, MSN, RN, PCNS-BC
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301-435-6837
Email:tjenkins@mail.nih.gov
Ruben Baler, PhD
National Institute on Drug Abuse (NIDA)
Telephone: 301-480-2733
Email:baler@nida.nih.gov
Merav Sabri, PhD
National Institute on Deafness and Other Communication Disorders (NIDCD)
Telephone: 301-827-0908
Email:merav.sabri@nih.gov
Alicia Chou, MS
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-594-4874
Email:alicia.chou@nih.gov
Aynur Unalp-Arida, MD, MSc, PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Telephone: 301-594-8879
Email: aynur.unalp-arida@nih.gov
Matthew Rudorfer, MD
National Institute of Mental Health (NIMH)
Telephone: 301-443-1111
Email: mrudorfe@mail.nih.gov
Lindsey Martin, PhD
National Institute of Environmental Health Sciences (NIEHS)
Telephone: 984-287-4036
Email: lindsey.martin@nih.gov
Nancy Jones, PhD, MA
National Institute on Minority Health and Health Disparities (NIMHD)
Telephone: 301-594-8945
Email: jonesna@nimhd.nih.gov
Adam L. Hartman, MD
National Institute of Neurological Disorders and Stroke (NINDS)
Telephone: 301-496-9135
Email: adam.hartman@nih.gov
Karen Kehl, PhD, RN, FPCN
National Institute of Nursing Research (NINR)
Telephone: 301-594-8010
Email: karen.kehl@nih.gov
Christopher Barnhart, PhD
Sexual & Gender Minority Research Office (SGMRO)
Telephone: 301-594-8983
Email:christopher.barnhart@nih.gov
Meryl Sufian, PhD
National Library of Medicine (NLM)
Telephone: 301-761-6249
Email: sufianm@mail.nih.gov
Jamie Marshell White, MS
Office of Research on Women's Health (ORWH)
Telephone: 301-496-9200
Email: jamie.white@nih.gov
Juliana M. Blome, PhD, MPH
Tribal Health Research Office (THRO)
Telephone: 240-338-8464
Email: juliana.blome@nih.gov
Shu Hui Chen, PhD
Office of Data Science Strategy (ODSS)
Telephone: 301-402-5392
Email: shuhui.chen@nih.gov
Peer Review Contact(s)
Not Applicable
Financial/Grants Management Contact(s)
Bruce Butrum
Fogarty International Center (FIC)
Telephone: 301-496-2075
Email: butrumb@mail.nih.gov
Matt Zeback
National Center for Advancing Translational Sciences (NCATS)
Telephone: 301-451-8309
Email: matthew.zeback@nih.gov
Debbie Chen
National Center for Complementary and Integrative Health (NCCIH)
Telephone: 301-594-3788
Email: debbie.chen@nih.gov
Crystal Wolfrey
National Cancer Institute (NCI)
Telephone: 240-276-6277
Email:wolfreyc@mail.nih.gov
Karen Robinson Smith
National Eye Institute (NEI)
Telephone: 301-435-8178
Email: kyr@nei.nih.gov
Deanna Ingersoll
National Human Genome Research Institute (NHGRI)
Telephone: 301-435-7858
Email: deanna.ingersoll@nih.gov
Alyse Burton
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: 301-827-8019
Email: burtonam@mail.nih.gov
Jeff Ball
National Institute on Aging (NIA)
Telephone: 301-403-7736
Email: ballj@nia.nih.gov
Judy Fox
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Telephone: 301-443-4704
Email: jfox@mail.nih.gov
Ann Devine
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-669-2988
Email:ann.devine@niaid.nih.gov
Leslie Littlejohn
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Telephone: 301-594-5055
Email: leslie.littlejohn@nih.gov
Monique Binger, PhD
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Telephone: 301-451-4797
Email: monique.binger@nih.gov
Margaret Young
Eunice Kennedy ShriverNational Institute of Child Health and Human Development (NICHD)
Telephone: 301-642-4552
Email:margaret.young@nih.gov
Pamela G. Fleming
National Institute on Drug Abuse (NIDA)
Telephone: 301-480-1159
Email:pfleming@nida.nih.gov
Christopher Myers
National Institute on Deafness and Other Communication Disorders (NIDCD)
Telephone: 301-435-0713
Email:myersc@mail.nih.gov
Diana Rutberg, MBA
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-594-4798
Email:rutbergd@mail.nih.gov
Gabriel Hidalgo
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone 301-827-4630
Email:gabriel.hidalgo@nih.gov
Thuthuy Nguyen
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Telephone: 301-594-8825
Email: thuthuynguyen@niddk.nih.gov
Jenny L Greer
National Institute of Environmental Health Sciences (NIEHS)
Telephone: 984-287-3332
Email: jenny.greer@nih.gov
Tamara Kees
National Institute of Mental Health (NIMH)
Telephone: 301-443-8811
Email: tkees@mail.nih.gov
Priscilla Grant, JD
National Institute on Minority Health and Health Disparities (NIMHD)
Telephone: 301-594-8412
Email: pg38h@nih.gov
Chief Grants Management Officer
National Institute of Neurological Disorders and Stroke (NINDS)
Email: ChiefGrantsManagementOfficer@ninds.nih.gov
Ronald Wertz
National Institute of Nursing Research (NINR)
Telephone: 301-594-2807
Email: wertzr@mail.nih.gov
Samantha J Tempchin
National Library of Medicine (NLM)
Telephone: 301-496-4222
Email: tempchins@mail.nih.gov