Notice of Intent to Publish a Funding Opportunity Announcement for RADx Tribal Data Repository
Notice Number:

Key Dates

Release Date:
February 11, 2022
Estimated Publication Date of Funding Opportunity Announcement:
February 25, 2022
First Estimated Application Due Date:
May 25, 2022
Earliest Estimated Award Date:
September 30, 2022
Earliest Estimated Start Date:
October 21, 2022
Related Announcements
Issued by

Office of The Director, National Institutes of Health (OD)


The purpose of this Notice is to announce that the NIH Office of the Director intends to publish a funding opportunity announcement in the winter of 2022 to support a Rapid Acceleration of Diagnostics (RADx®) Tribal Data Repository (RADx TDR) for American Indian and Alaska Native (AI/AN) data collected from projects supported by the RADx initiative. The RADx TDR data will allow better understanding of the impact of COVID-19, support research to better inform and develop policies to address current and future pandemics, and support and promote researchers, including AI/AN researchers The RADx TDR is intended to be an independent, tribally directed research data repository using a sovereignty-based governance structure that will provide responsible data sharing and access to researchers and their collaborators who are generating or interested in working with RADx AI/AN research data. The RADx TDR will collaborate with the RADx-Underserved Populations Coordination and Data Collection Center (RADx-UP CDCC). The TDR will not hold any biological samples.

This FOA will use the U24 Resource-Related Research Projects-Cooperative Agreement activity code and seeks to fund a single RADx TDR. The funding for this award is provided from the American Rescue Plan Act of 2021.

The RADx TDR will recognize the sovereignty of Tribal Nations by providing overarching tribally based governance, support and guidance in the following two domains: (1) Administrative Operations and Logistics and (2) Data Collection, Integration and Data Sharing. RADx funded projects are required to collect all NIH RADx Required Common Data Elements and share these data at a cadence defined by NIH and Tribal Nation data transfer and use agreements throughout the life of the project. The RADx TDR will receive RADx data directly from RADx AI/AN projects for deposit into the RADx TDR. The RADx TDR will facilitate RADx collaborative research by providing organizational and analytical infrastructure and expertise, supporting data integration and analysis, accessing AI/AN RADx research data, and coordinating across specific AI/AN populations participating in the NIH-supported RADx initiatives that are developing and validating new COVID-19 testing technologies.

Research Initiative Details

This Notice encourages applications from organizations supporting investigators:

  • with a documented history of working with tribal Nations and experience in Tribal sovereignty issues related to data ownership and governance, data sharing, and
  • with expertise and insights into this area of data science and the establishment of independently governed data repositories .

In addition, collaborative investigations combining expertise in biostatistics, epidemiology, artificial intelligence (AI), data aggregation and harmonization, social determinants of health disparities, resilience, and tribal sovereignty, among others, will be encouraged.

Funding Information
Estimated Total Funding

NIH will commit up to $12 million in total costs in FY 2022 and the project will be supported for four years.

Expected Number of Awards

NIH intends to fund one award.

Estimated Award Ceiling

Up to $3 million in total costs will be funded per year.

Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
Indian/Native American Tribal Government (Federally Recognized)
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization

Applications are not being solicited at this time. 


Please direct all inquiries to:

Dorothy Castille, Ph.D.

National Institute on Minority Health and Health Disparities