December 2, 2021
NOT-OD-22-209 - Notice of Early Termination of NOT-OD-22-031, “Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional)”
NOT-GM-22-023 - Notice of NIGMS Participation in NOT-OD-22-031, "Notice of Special Interest (NOSI): Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional)"
PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
NOT-OD-20-048 - Notice of Special Interest (NOSI): Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional)
Office of Research on Women's Health (ORWH)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
National Human Genome Research Institute (NHGRI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke ( NINDS
National Institute of Nursing Research (NINR)
National Center for Complementary and Integrative Health (NCCIH)
National Center for Advancing Translational Sciences (NCATS)
National Cancer Institute (NCI)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)
Sexual and Gender Minority Research Office (SGMRO)
The Office of Research on Women's Health (ORWH) announces the availability of administrative supplements to support research highlighting health inequities among women in the US who are underrepresented, understudied, and underreported (U3) in biomedical research. Robust studies exploring sex and gender influences and social determinants of health are needed to reduce inequities. The proposed research must address at least one objective from strategic goals 1, 2 or 3 of the “2019-2023 Trans-NIH Strategic Plan for Women's Health Research, Advancing Science for the Health of Women."
Women account for over half of the US population according to the US Census Bureau. Women and girls in certain subpopulations bear a disproportionate burden of health risks, disease prevalence and poorer health outcomes, including but not limited to NIH designated health disparities populations, homeless, institutionalized, or incarcerated persons, persons having physical, intellectual, or sensory disabilities, and underserved immigrants. Additionally, underrepresentation in data reporting and biomedical research, hinders unique opportunities to learn more about associations between personal identity, sociocultural factors, and health.
There is a complex intersection of internal (e.g., genetics), and external institutional and structural forces (e.g., social determinants of health, experiences of trauma) that play a role in the health status, disease presentation, treatment responses and health-related quality of life of women across the life course. In 2014, ORWH published "The Women of Color Health Data Book, 4th edition" (https://orwh.od.nih.gov/sites/orwh/files/docs/WoC-Databook-FINAL.pdf), which consists of US government sourced, population-based health and disease data. It highlights the urgent need to improve understanding of the etiologies of health and health care inequities among populations of women and the mechanisms by which social determinants of health (e.g., racism) contributes to them.
This NOSI encourages rigorous experimental designs and the implementation of collaborative interdisciplinary research on the common causes and pathways of ill health and disease, differential risk, morbidity, and mortality, across socioecological domains and levels of influence. It additionally encourages thoughtful incorporation of intersectionality into research applying the multidimensional research framework as such has the greatest potential to promote the creation of evidence to best meet group- and population-level needs with approaches that are culturally and contextually relevant. To strengthen and accelerate multidisciplinary disparities research in women’s health, this opportunity also encourages the partnership of both junior and senior investigators and experienced women’s health researchers with researchers with expertise in health disparities. Lastly, the COVID-19 pandemic has magnified longstanding challenges and barriers faced by women and girls, with respect to the gendered work, lower paid positions/economic instability, gender-based violence and unsafe housing. This NOSI will support work to address these challenges including when they intersect with bias and discrimination associated with race, sexual orientation, disability, age, and socioeconomic status as well.
Specific Areas of Research Interest
This NOSI will support projects highlighting common sources of disparities in women and girls’ health with a specific emphasis on those that integrate measures beyond the individual level and consider perspectives from multiple disciplines. A broad range of research topics studied at the preclinical, clinical, behavioral, and translational levels are encouraged. Proposals incorporating multilevel interventions, using community-engaged approaches, and focusing on one or more NIH-designated health disparities populations are also desired.
Topics of interest include, but are not limited to:
Only electronically submitted applications will be accepted.
Note: Specific aims added to the parent grant per SARS-CoV-2/COVID-19 Competitive Revisions process are considered as part of the parent application and are eligible to apply for a supplement under this NOSI.
PDs/PIs of above-mentioned activity codes must also fulfill all the following requirements, otherwise their applications will be deemed non-responsive to this NOSI.
Only one U3 Administrative Supplement award, per period of performance, is permitted to a peer-reviewed NIH funded grant. An exception may be given for proposals studying SARS-CoV-2 or COVID-19, please contact the ORWH scientific contact for approval.
Scientific Review Process
The NIH program staff will conduct administrative reviews of the application submissions; the most meritorious applications will receive funding consideration pending availability of funds.
Description of circumstances for which administrative supplements are available.
Application and Submission Information
Damiya (Miya) Whitaker, PsyD, MA
Office of Research on Women’s Health (ORWH)
Email contact firstname.lastname@example.org