Notice of Special Interest (NOSI): Research Supplements to Promote Diversity in Environmental influences on Child Health Outcomes (ECHO) Program Research (Admin Supp - Clinical Trial Not Allowed)
Notice Number:

Key Dates

Release Date:

April 16, 2021

First Available Due Date:
May 26, 2021
Expiration Date:
May 27, 2021

Related Announcements

PA-21-071 - Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)

Issued by

Office of The Director, National Institutes of Health (OD)


The purpose of this NOSI is to encourage eligible grantees to apply for this administrative supplement aimed at fostering diversity in the child health research workforce within the ECHO Program.

The ECHO Program’s mission is to enhance the health of children for generations to come. Understanding the effects of environmental exposures on child health and development is a priority for the NIH.

As stated in the Notice of NIH’s Interest in Diversity, NOT-OD-20-031, “the NIH’s ability to help ensure that the nation remains a global leader in scientific discovery and innovation is dependent upon a pool of highly talented scientists from diverse backgrounds.” Supplements to promote diversity in health-related research help address underrepresentation in the scientific research workforce, which is a key component of the NIH strategy to identify, develop, support and maintain the quality of our scientific human capital.

Inclusion of diverse perspectives can help ECHO better address children’s health. The ECHO Program is committed to fostering a diverse workforce, including individuals from groups identified as underrepresented, and is well-poised to support talented individuals from diverse backgrounds.

As such, the ECHO Program Office is pleased to offer diversity supplements for Graduate (Predoctoral) and Health Professional Students and Individuals in Postdoctoral Training and Clinical Fellows Training in Medical Fields from ECHO cohort grantees and the Institutional Development Awards (IDeA) States Pediatric Clinical Trials Network (ISPCTN).

Please see the Notice of NIH's Interest in Diversity NOT-OD-20-031 for examples of  underrepresented populations in the US research enterprise. ECHO awardees should apply under the stipulations in PA-21-071 Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed). The candidate’s proposed research experience must be an integral part of the approved, ongoing research of the parent award, and it must have the potential to contribute significantly to the research career development of the candidate. Supplements are for a two-year period. Recipients must comply with all ECHO policies.

Research Topics: Applications must 1) address the mission of ECHO, 2) contribute to at least one of the ECHO Program’s five key pediatric outcomes: pre-, peri-, and postnatal, upper and lower airway, obesity, neurodevelopment, and positive health, and 3) contribute to ECHO-wide Cohort science or completed, ongoing, or planned ISPCTN clinical trials.

For ISPTCN candidates, appropriate research topics could include but are not limited to secondary analysis of data resulting from ongoing or completed ISPCTN trials; qualitative and quantitative studies designed to support current or future trials in IDeA States (e.g., factors affecting rates of informed consent at different sites; factors influencing the accuracy of extraction of research data for analyses,.).

Eligibility: Candidates must be enrolled in a doctoral degree program toward completion of a terminal scientific degree (e.g., Ph.D., Sc.D., M.D.) or in Postdoctoral Training or engaged in Postdoctoral, Internship, Residency or Clinical Fellowship Training programs in any of medical, nursing, or allied health topics. Please note that faculty members are not eligible.

Principal Investigators from the following ECHO Components may apply through the parent grant: ISPCTN Clinical Site awards, Cohort awards, PRO Core, CC, DAC, and ISPCTN DCOC, under the stipulations in PA 21-071 Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed). Applications for the Supplement may propose no more than one candidate per award.

Review Criteria: The ECHO Program Office will determine the merit of applications based on evaluation of the following three equally weighted components:

  • Candidate
  • Mentoring Plan
  • Research Proposal

Application and Submission Information

Application Due Date: May 26, 2021.

The Authorized Organizational Representative from your institution must submit the application electronically to the NIH following the instructions in the Funding Opportunity Announcement (FOA):

PA 21-071 Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)

For funding consideration, applicants must include NOT-OD-21-093 in the Agency Routing Identifier field (Box 4.b) of the SF 424 (R&R) Form.

The ECHO Program Office will not consider applications that fail to meet the terms of this Notice.

To facilitate efficient processing of the request, the ECHO Program Office strongly encourages applicants to notify one of the contacts listed below when they have submitted a response to this NOSI.


Susan A. Laessig, Ph.D. (ECHO Cohorts);
Tonse Raju, MD (ISPCTN);
Environmental influences on Child Health Outcomes (ECHO), NIH Office of the Director

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