NIH Implementation of the Revised Federal-wide Research Terms and Conditions
Notice Number:

Key Dates

Release Date:

November 17, 2020

Related Announcements


Issued by

Office of The Director, National Institutes of Health (OD)


The Office of Management and Budget (OMB) mandated awarding agencies adopt recent revisions to 2 CFR §200; Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards (Uniform Guidance) effective November 12, 2020. Accordingly, the Federal-wide Research Terms and Conditions (RTCs) have been revised by the participating agencies, including NIH, for consistency with the revised 2 CFR §200. The National Science Foundation hosts and maintains the RTC website on behalf of all of the participating agencies.

As outlined in the NIH Agency Implementation Statement, effective November 12th, 2020, the RTCs apply to all NIH grants and cooperative agreements with the exceptions noted in the NIH Agency Specific Requirements. NIH implementation of these Federal-wide RTCs is outlined in the NIH Grants Policy Statement, Section 3.1, and fully incorporates the revised 2 CFR §200. The RTCs serve as standard terms and conditions of all NIH awards. There are no significant changes in the requirements or terms and conditions for NIH recipients. Recipients are encouraged to review the updated documents, which include the RTC overlay, the Prior Approval Matrix, Subaward Requirements, National Policy Requirements, and the NIH Agency Specific Requirements.

Please note that the previous version of the RTCs incorporated the full set of OMB Frequently Asked Questions (FAQs) by reference. The FAQs have not yet been updated to align with 2 CFR §200, and, as such have been deleted from the RTC Overlay.


Please direct all inquiries to:

Division of Grants Policy
Office of Policy for Extramural Research Administration

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices