Publication of the Revised NIH Grants Policy Statement (Rev. 10/1/2010): Policy Changes, Clarifications and Document Enhancements

Notice Number:  NOT-OD-11-003

Key Dates

Release Date: October 15, 2010   

Issued by

National Institutes of Health (NIH)


The National Institutes of Health (NIH) announces the publication of the revised NIH Grants Policy Statement (NIHGPS, rev. 10/1/2010).  This revision is applicable to all NIH grants and cooperative agreements with budget periods beginning on or after October 1, 2010. This revision supersedes, in its entirety, the NIH Grants Policy Statement (12/03) as a standard term and condition of award.  However, the December 2003 NIHGPS continues to be the standard term and condition for all NIH grants and cooperative agreements with budget periods that began between December 1, 2003 and September 30, 2010.

The NIHGPS provides both up-to-date policy guidance that serves as NIH standard terms and conditions of awards for grants and cooperative agreements, and extensive guidance to individuals that are interested in pursuing NIH grants.

This revision incorporates NIH policy changes since the December 2003 version, policy clarifications, public policy changes, terminology changes, new chapters, chapter revisions, reorganization of the document, as well as other document enhancements such as a new chapter numbering schema. Some sections have been rewritten to provide clarity; however, the overall policies in these sections have not changed. The document is available in the following electronic formats: HTML and PDF

The link to the 12/03 NIHGPS and all previous versions will remain the same.

NIH will continue to publish interim grants policy changes through the issuance of NIH Guide Notices found at   Each change will be described, including its applicability and effective date; and the necessary language to implement it as a term or condition of award provided.

A document is available that summarizes the significant changes that are implemented with the October 1, 2010 NIHGPS (MS Word - 252 KB).


Please direct all inquiries to:

Division of Grants Policy
Office of Policy for Extramural Research Administration
National Institutes of Health
6705 Rockledge Drive, Suite 350
Bethesda, MD 20892

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.