Extramural Loan Repayment Program for Clinical Researchers (LRP-CR): Program Specific Information

Notice Number: NOT-OD-09-108

Update: The following update relating to this announcement has been issued:

  • July 8, 2010 - See Notice NOT-OD-10-106 This Notice replaces and provides program specific information for Extramural Loan Repayment Program for Clinical Researchers (LRP-CR).
Catalog of Federal Domestic Assistance Number

Key Dates
Release Date: June 18, 2009

Issued by
National Institutes of Health (NIH), (http://www.nih.gov)


This Notice replaces NOT-OD-08-088, and provides program specific information for Extramural Loan Repayment Program for Clinical Researchers (LRP-CR). Applicants must refer to the general LRP Notice providing information on the application period, general eligibility, annual receipt and review schedule, application material, evaluation criteria, and program administration details: NIH Extramural Loan Repayment Programs (LRP), NOT-OD-09-107. Through this Notice, the NIH invites qualified health professionals to apply for participation in the LRP-CR.


The objective of the LRP-CR program is to recruit and retain highly qualified health professionals as clinical investigators.

NIH defines clinical research as patient-oriented clinical research conducted with human subjects, or research on the causes and consequences of disease in human populations involving material of human origin (such as tissue specimens and cognitive phenomena) for which an investigator or colleague directly interacts with human subjects in an outpatient or inpatient setting to clarify a problem in human physiology, pathophysiology or disease, or epidemiological or behavioral studies, outcomes research or health services research, or developing new technologies, therapeutic interventions, or clinical trials."


In addition to the eligibility criteria outlined in the general Notice (see: NIH Extramural Loan Repayment Programs, NOT-OD-09-107), applicants for LRP-CR must have an M.D., Ph.D., Pharm. D., Psy.D., D.O., D.D.S., D.M.D., D.P.M., D.C., N.D., or equivalent doctoral degree from an accredited institution, and must engage in qualified clinical research as defined above.


The NIH intends to commit approximately $42 million annually to fund LRP-CR contracts.


Awards are made pursuant to the Public Health Improvement Act of November 2000 (Public Law 106-505), also known as the Clinical Research Enhancement Act, which added Section 487F of the Public Health Service (PHS) Act (42 U.S.C. 288-5a). The Federal Debt Collection Procedures Act of 1990, contained in Public Law 101-647, requires that an individual who has a judgment lien against his/her property for a debt to the United States shall not be eligible to receive funds directly from the Federal government in any program, except funds to which the debtor is entitled as a beneficiary, until the judgment is paid in full or otherwise satisfied (28 USC 3201).