NIH/AHRQ Reminder to Use Updated SF424 (R&R) and Agency-Specific Electronic Forms in Reposted FOAs

Notice Number: NOT-OD-06-085

Key Dates
Release Date: July 14, 2006

Update: The following update relating to this announcement has been issued:

  • July 27, 2006 (NOT-OD-06-087) - See SF424(R&R) Research & Related Senior/Key Person Profile Form Issue – Workaround for Adding More Than Eight Senior/Key Persons.

Issued by
National Institutes of Health (NIH), (
Agency for Healthcare Research and Quality (AHRQ), and NIH/AHRQ recently announced implementation plans for Version 2 of the SF424 (R&R) and agency-specific (labeled PHS 398) electronic application forms (see NOT-OD-06-078).

As previously announced, the timetable for Funding Opportunity Announcements (FOAs) updates to use Version 2 forms is:

Release/Posted Date of FOA

Expiration Date

Grant Mechanism

Use New Forms

Before June 15, 2006

On/Before Dec. 31,2006

All mechanisms

N/A - will be allowed to close gracefully with no form change.

Before June 15, 2006

After Dec. 31, 2006

R03, R15, R21, R21/R33, R33, R34, R36 and XO1

After July 18, 2006

Before June 15, 2006

After Dec. 31, 2006

SBIR/STTR (R43, R44, R41, R42), R13/U13

After Sept. 15, 2006

On/After June 15, 2006


All mechanisms

Immediately – initial posting will include new form package.

We have completed the first set of updates (highlighted above) to FOAs.

Important notes:

  • We have added the Version 2 form packages to existing FOAs, so the opportunity numbers have not changed.
  • Once FOAs are updated with the new Version 2 form package, will no longer accept applications with the older package. You must use the updated form package. Any application “in the works” will need to be moved to the new form package (i.e., download new forms and cut-and-paste content from one form to the other).
  • If your business office provides to Principal Investigators versions of the form packages that are pre-populated with your organization’s information, you will want to make sure your form package templates are updated.
  • To assist you in identifying the form version used to create an application package, NIH/AHRQ have populated the Competition ID of new forms packages with the label “VERSION-2-FORMS”. The Competition ID appears at the top of the page when you open an application package with the PureEdge viewer. Similarly, the appropriate application guides will be labeled Version 1 and Version 2 on the cover page and within the footers. The SF424 (R&R) Application and Electronic Submission Information page includes links to Version 1 and Version 2 of the Application Guide and a short overview of notable changes in each version.
  • There will be a short period of time when both the old and new form packages will be available for download. Whenever there is a choice, the package labeled “VERSION-2-FORMS” in the Competition ID field should be used. To help in the transition, NIH has developed a splash screen that will alert users to select the Version 2 package. However, the splash screen will be only visible when using the NIH Guide and the download button from within the NIH Guide FOA to find and download opportunities.

The following FOAs had receipt dates within the next several weeks; we have chosen to defer their update until September:

  • PAR-06-095           NIDCD Translational Research Grants (R21)
  • PAR-06-118           AHRQ Grants for Health Services Research Dissertation (R36)
  • PAR-06-217           Mental Health Dissertation Research Grant To Increase Diversity (R36)
  • PAR-06-293           Quick-Trials for Imaging and Image-Guided Interventions: Exploratory Grants (R21)
  • PAR-06-294           Small Grants Program for Cancer Epidemiology (R03)
  • PAR-06-313           Cancer Prevention Research Small Grant Program (R03)
  • PAR-06-420           Brain Disorders in the Developing World: Research Across the Lifespan (R21)
  • PAR-06-448           AHRQ Small Research Grant Program (R03) 
  • PAR-06-451           Quick-Trials for Novel Cancer Therapies: Exploratory Grants (R21)
  • PAR-06-458           Small Grants for Behavioral Research in Cancer Control (R03)
  • PAR-06-460           NINDS Clinical Trial Planning Grant (R34)

In addition, one AHRQ R13/U13 FOA has been included in the current set of updates:

  • PA-06-378              AHRQ Grant Program for Large Conference Support (R13) and (U13)

The following resources continue to be available for assistance in the electronic submission of grant applications to NIH/AHRQ through

General Information: Customer Support

Phone: 800-518-4726
Hours: M-F 7:00 a.m.-9:00 p.m. ET
eRA Service Desk
Phone: 301-402-7469 or 866-504-9552 (Toll Free)
TTY: 301-451-5939
Hours: M-F 7:00 a.m.– 8:00 p.m


Inquiries regarding this Notice should be directed to:

Grants Info
Office of Extramural Research
National Institutes of Health
Phone: 301-945-7573
TTY: 301-451-5936