Reminder for Applicants Considering the Multiple PI Option

Notice Number: NOT-OD-06-074

Key Dates
Release Date: June 7, 2006

Issued by
National Institutes of Health (NIH), (


Applicants are reminded that the National Institutes of Health is conducting a pilot on the option to include more than one Principal Investigator (PI) on a grant application.  The programs participating in this pilot are listed on the Multiple PI website at   The multiple PI option is available only for programs involved in the pilot and listed on the website.  

As outlined in the May 11 NIH Guide Notice NOT-OD-O6-069 at, applicants should not use the multiple PI option unless they are responding to one of the programs included in the pilot.  Specifically, applicants should NOT include the PHS 398 Form Page 1- continued, nor a Multiple PI Leadership Plan as part of the Research Plan unless they are specifically responding to an announcement that includes Multiple PI as an option. Applications submitted in response to funding announcements that are not a part of the pilot but include this information may be delayed or in some cases may not be reviewed.   

Applicants that are participating in the pilot initiatives are reminded that all participating PIs need to be registered in the NIH Commons at prior to submission.  Also, applicants electing to use the multiple PI option must include a leadership plan as Section I of the Research Plan in the PHS 398 application kit.  The application form can be found at
Questions about the Multiple PI pilot can be sent to

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

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