Notice of Intent to Publish a Notice of Funding Opportunity Announcement for NINDS Program Project Grant (P01 Clinical Trial Optional)
Notice Number:

Key Dates

Release Date:
February 28, 2024
Estimated Publication Date of Notice of Funding Opportunity :
April 01, 2024
First Estimated Application Due Date:
May 25, 2024
Earliest Estimated Award Date:
January 15, 2025
Earliest Estimated Start Date:
February 15, 2025
Related Announcements
  • April 5, 2021 - NINDS Program Project Grant (P01 Clinical Trial Optional). See NOFO PAR-21-181.
Issued by

National Institute of Neurological Disorders and Stroke (NINDS)


The National Institute of Neurological Disorders and Stroke (NINDS), intends to publish a reissue Notice of Funding Opportunity (NOFO) to solicit applications for innovative, interactive research to answer significant scientific questions that are important for the mission of NINDS, via a synergistic collaboration between outstanding scientists who might not otherwise collaborate. The program project grant is designed to support research in which the funding of several interdependent highly meritorious projects as a group offers significant scientific advantages over support of these same projects as individual research grants. .

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The NOFO is expected to be published in April 2024 with an expected application due dates in May and September 2024. 

NINDS will not have any receipt dates after September 2024, thus ending the program. 

This NOFO will utilize the P01 activity code. Details of the planned NOFO are provided below.

Research Initiative Details

The National Institute of Neurological Disorders and Stroke's program project grants (PPG) support investigator-initiated research programs, consisting of three or more highly interdependent projects, in which a team of investigators works in a clearly defined area of mutual scientific interest. In a program project, there should be a unifying, well-defined goal or targeted area of research to which each project relates and contributes, thereby producing a synergistic and collaborative research environment that allows each research project to share the creative strengths of the others. Programs should present a compelling case in support of interrelated projects and collaborating investigators will yield results beyond those achievable if each project were pursued separately and without formal interaction among the participating investigators. The applicants should consider why the program project is required to achieve the proposed research goals, how reaching these goals may transform the field, and why the goals of the component projects cannot be achieved without significant contributions from the other components. Overall, the applicants should demonstrate a clear and compelling case that the component projects require one another and the shared core facilities.

Funding Information

Estimated Total Funding


Expected Number of Awards
Estimated Award Ceiling


Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 


Alisa Schaefer, Ph.D.
National Institute of Neurological Disorders and Stroke (NINDS)