Request for Information: Soliciting Input on a Proposed Traumatic Brain Injury (TBI) Classification System
Notice Number:

Key Dates

Release Date:

January 9, 2024

Response Date:
February 23, 2024

Related Announcements


Issued by

National Institute of Neurological Disorders and Stroke (NINDS)


The purpose of this time-sensitive Request for Information (RFI) is to seek public input on a proposed updated traumatic brain injury (TBI) classification, characterization, and nomenclature system that is being developed by over 80 subject matter experts within the scientific community. This proposed system is for research purposes only. Public input is requested from families, caregivers, advocates, scientists, clinicians, individuals that have sustained a TBI of any severity, and the broader community.

Background and Information Requested

The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), is convening a workshop on January 22 and 23, 2024 to review data from previous and existing clinical studies and propose a more precise and evidence-based classification system – beyond the “mild, moderate, and severe” terms that are currently used. The development of a more precise classification system will accelerate research progress and significantly advance the field.

Responses to this RFI will be shared with working groups of scientists, clinicians, advocates, and people with lived experiences, including those that have sustained a TBI. These parties will use this information, along with their own knowledge of the field to refine and update the current TBI classification system. During the workshop, these working groups will present their ideas based on collected input thus far and the current research landscape . The workshop is titled: “NINDS TBI Classification and Nomenclature Workshop” and will be free to attend, open to the public and scientific community, and will include opportunities for feedback and recommendations from the public  on the proposed system,  future research priorities, and considerations. After the meeting, the working groups may revise and modify the recommendations and research priorities while considering public input. The revised draft of the proposed system and research recommendations will then be posted  online for public comment.

How to Submit a Response

Responses to this RFI must be submitted electronically using the web-based form found here: (Feedback - NINDS Traumatic Brain Injury (TBI) Classification and Nomenclature Workshop (

To ensure full consideration, your responses must be received by 2/23/2024. Responses may be submitted after this date, but we cannot guarantee full incorporation.

Responses are voluntary and may be submitted anonymously. Responders are advised that the U.S. Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. Submitted information will not be considered confidential. Do not include any proprietary, classified, confidential, trade secret, or sensitive information in your response. Responses may be shared publicly on an NIH website, and the provided information may appear in summary form in reports or other publicly accessible resources. Please do not include any personally identifiable or other information that you do not wish to make public. The U.S. Government will use the information submitted in response to this RFI at its discretion.

This RFI is for information and planning purposes only and shall not be construed as a solicitation, grant, or cooperative agreement, or as an obligation on the part of the U.S. Government, the NIH, or individual NIH Institutes and Centers to provide support for any ideas identified in response to it. The U.S. Government will not pay for the preparation of any information submitted or for the U.S. Governments’ use of such information. No basis for claims against the U.S. Government shall arise as a result of a response to this RFI or from the U.S. Governments’ use of such information.


Please direct all inquiries to:

Name: TBI Team 

IC Name: National Institute of Neurological Disorders and Stroke