Notice of Intent to Publish a Funding Opportunity Announcement for NIH Blueprint for Neuroscience Research Short Courses in Neurotherapeutics Development (R25 Clinical Trial Not Allowed)
Notice Number:

Key Dates

Release Date:
September 10, 2021
Estimated Publication Date of Funding Opportunity Announcement:
September 24, 2021
First Estimated Application Due Date:
November 01, 2021
Earliest Estimated Award Date:
June 01, 2022
Earliest Estimated Start Date:
July 01, 2022
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Issued by

National Institute of Neurological Disorders and Stroke (NINDS)

National Eye Institute (NEI)

National Institute on Aging (NIA)

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

National Institute of Dental and Craniofacial Research (NIDCR)

National Institute on Drug Abuse (NIDA)

National Institute of Environmental Health Sciences (NIEHS)

National Institute of Mental Health (NIMH)

National Center for Complementary and Integrative Health (NCCIH)


The National Institutes of Health (NIH) Blueprint for Neuroscience Research intends to reissue a Funding Opportunity Announcement (FOA) for receipt of new applications for its training program in neurotherapeutics discovery and development. This short course initiative was one of several strategies to address the Grand Challenge for Neurotherapeutics. As such, short courses developed under this initiative must have a neuroscience focus and must address the unique challenges inherent in developing treatments for nervous system disorders, such as blood-brain barrier penetration and limitations of animal and cell-based models for evaluating novel treatments for neurological and behavioral disorders. The courses also must be broadly applicable to diseases of the nervous system, rather than focusing on a single disease or disease class.

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH.  The over-arching goal of this NIH Blueprint for Neuroscience Research R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The FOA is expected to be published in Fall 2021 with an expected application due date in Winter 2021.

This FOA will utilize the R25 activity code. Details of the planned FOA are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insights into this area of neurotherapeutics training to begin to consider applying for this new FOA.

To accomplish the stated over-arching goal, the upcoming FOA will support creative educational activities with a primary focus on Courses for Skills Development. The plan FOA will solicit Research Education Grant (R25) applications to develop and implement short courses on neurotherapeutics development for academic neuroscientists. The short courses should provide participants with a sufficient overview of the neurotherapeutics development process to (1) understand the steps required for therapeutics development, (2) anticipate and overcome common challenges in the process, and (3) interact effectively with collaborators who have expertise in various aspects of therapeutics development. The short courses should primarily target independent academic neuroscience researchers and senior post-doctoral fellows interested in incorporating treatment development into their research programs..

The future FOA is expected to continue the overarching objective of the 2016 NIH Blueprint R25 FOA: RFA-NS-16-017.

Funding Information
Estimated Total Funding


Expected Number of Awards
Estimated Award Ceiling


Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Private Institution of Higher Education
Public/State Controlled Institution of Higher Education

Applications are not being solicited at this time. 


Please direct all inquiries to:

Charles Cywin, Ph.D.

National Institute of Neurological Disorders and Stroke (NINDS)



Weekly TOC for this Announcement
NIH Funding Opportunities and Notices