Notice of Intent to Publish a Limited Competition Announcement for Applications for Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (U54)

Notice Number: NOT-NS-14-042

Key Dates
Release Date: August 8, 2014
Estimated Publication Date of Announcement: October 2014  
First Estimated Application Due Date: December 2014 
Earliest Estimated Award Date: July 2015 
Earliest Estimated Start Date: July 2015 

Related Announcements

Issued by
National Institute of Neurological Disorders and Stroke (NINDS)
National Center for Advancing Translational Sciences (NCATS)


The National Institute of Neurological Disorders and Stroke (NINDS), with the Office of Rare Diseases Research (ORDR) at the National Center for Advancing Translational Sciences (NCATS), intend to publish a Funding Opportunity Announcement (FOA) to solicit applications for research on rare diseases via the Rare Diseases Clinical Research Network.  This FOA will be a limited competition available only to Program Directors/Principal Investigators who received a previous NINDS award under the Rare Disease Clinical Research Network program and who recently submitted a renewal (type 2) application in response to RFA-TR-13-002.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The FOA is expected to be published in the fall of 2014 with an anticipated application due date in December of 2014.

This FOA will utilize the U54 activity code. Details of the planned FOA are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insights into the area of rare neurological disorders to begin to consider applying for this limited competition FOA. The objective is to facilitate clinical research in rare diseases through support for: 1) collaborative clinical research in rare diseases, including longitudinal studies of individuals with rare diseases, clinical studies and/or phase I and II trials; 2) training of clinical investigators in rare diseases research; 3) pilot and demonstration projects; and 4) access to information related to rare diseases for basic and clinical researchers, academic and practicing physicians, patients, and the lay public.  The total project period for an application submitted in response to this FOA may not exceed 4 years.



Please direct all inquiries to:

Laura A. Mamounas, Ph.D.
National Institute of Neurological Disorders & Stroke (NINDS)
Telephone: 301-496-5745