Request for Information (RFI): Input on the European Multi-PART (Multicenter Preclinical Animal Research Team) planning effort to generate international preclinical stroke network infrastructure

Notice Number: NOT-NS-14-006

Key Dates
Release Date: January 16, 2014
Response Date: February 7, 2014

Related Announcements

Issued by
National Institute of Neurological Disorders and Stroke (NINDS)


The National Institute of Neurological Disorders and Stroke (NINDS) is requesting opinions from the US stroke research community regarding the European Multi-PART (Multicenter Preclinical Animal Research Team; initiative. 


Multi-PART is a planning effort intended to generate infrastructure for an international preclinical stroke network. Its overall objective is to develop the capacity to undertake international multicenter animal studies to improve the validity and generalizability of current preclinical research. The consortium, a group of internationally recognized scientists with broad and comprehensive expertise, proposes to perform preclinical studies with the same rigor and centralized coordination that characterize multicenter Phase III randomized controlled clinical trials in humans. Creating such a network was identified as a cross-cutting priority at the 2012 NINDS Stroke Research Priorities Meeting (see, for a description of the recommendations developed at that conference).

Request for Information

Investigators actively conducting stroke research are encouraged to provide a brief description (not to exceed 2 pages) of their view regarding the benefits and risks for US stroke investigators for participating in Multi-PART, area(s) of expertise in stroke research, and potential contribution to the Multi-PART planning effort.

How to Submit a Response

Responses will be accepted through February 7th, 2014. Electronic responses are preferred and may be addressed to (please include the Notice number, NOT-NS-14-006, in the subject line). Responses may also be sent by letter or fax to the following address:

Francesca Bosetti, Pharm.D., Ph.D.
Program Director,
Neural Environment Cluster
National Institute of Neurological Disorders and Stroke
National Institutes of Health
6001 Executive Blvd. Rm. 2115
Bethesda, MD 20892-9521
Fax: 301-402-2060

Responses to this RFI are voluntary, and will be reviewed by NINDS. This RFI is for planning purposes only, and is not a solicitation for applications or an obligation on the part of the United States (U.S.) Government to provide support for any ideas identified in response to it. Please note that the U.S. Government will not pay for the preparation of any comment submitted, or for the use of that comment.


Please direct all inquiries to:

Francesca Bosetti, Pharm.D., Ph.D.
National Institute of Neurological Disorders and Stroke (NINDS)
Phone: 301-496-1431