Release Date:  November 16, 2000

NOTICE:  NS-01-002

National Institute of Neurological Disorders and Stroke

The National Institute of Neurological Disorders and Stroke (NINDS) 
announces an administrative supplement program of up to $3 million in 
FY2001 to foster additional research on Parkinson"s Disease (PD) across 
a wide variety of scientific disciplines, and to allow investigators 
not currently working in PD to join the field.  This supplemental 
funding initiative is issued in response to recommendations in the 
Parkinson"s Disease Research Agenda, available on the website: calling 
for innovative funding mechanisms.  This program is intended to 
facilitate research within ongoing, peer-reviewed projects that have 
Specific Aims on PD, or Specific Aims within other areas that may 
translate to PD (see bullets below). These one-time supplements are 
intended to help grantees develop preliminary data for new R21"s or 
R01"s.  Principal Investigators (PIs) with Research Project (R01), 
Exploratory/Developmental (R21), FIRST (R29), Phase II SBIR (R44), 
Program Project (P01), and Specialized Center (P50 or U54) grants are 
eligible to apply.  To be eligible, projects must have a Project Period 
End Date of April 30, 2002, or later (a no-cost extension beyond that 
date does not confer eligibility).

Evidence should be presented that the results of the supplemental 
assistance will enhance the pursuit of Specific Aims of the research 
project, and be focused on Parkinson"s Disease, without constituting an 
expansion of scope.  Supplements are one-time awards and will not 
extend to subsequent years.

Specific examples of supplemental requests that may be considered 
include, but are not limited to:

o	Requests involving the basic cellular and molecular biology or 
basic pathophysiology of PD within existing PD grants.

o	Analysis of animal models, developed through existing grants on 
other disorders, for potential use in PD.  Models may include 

o	Requests within existing grants on the development of biomarkers 
or genetic tools in neurodegnerative diseases to include PD.

How to Apply: Submission of requests should be made electronically.  
Send an email message to: with the PI"s 
name (last, first) and grant number on the subject line.  Include the 
following items in an attached file in MSWord, WordPerfect, or PDF 

1) A cover page citing this NOTICE and requesting an administrative 
supplement. Include the PI name, grant number and title, amount 
requested, name and title of the institutional official, and phone, 
email, and address information for the PI and institutional official.  
For P01s, P50s, and U54s the overall project PI must submit the request 
for a supplement. 

2) A letter (5-page limit) describing the project, including an 
abstract, a description of the proposed experiments and their 
relationship to the original project Specific Aims, a discussion of the 
significance of the results to PD, and a budget with justifications.

3) Biographical sketch of the PI.

4) Specific Aims of the original grant.

5) Documentation of co-funding, if appropriate.

In addition, an original cover page signed by the PI and countersigned 
by the institutional official should be submitted by mail.  This is 
required for the issuance of an award, and should be sent to the NINDS 
staff contact for application issues, Dr. Carlos Pena, listed at the 
end of this notice.  The cover page is not the cover page of the 
original grant, but is specific for this request.  It should be 
formatted as a memo or letter and provide the information listed above.  
PIs should not submit a request electronically until the institutional 
business office has reviewed and approved the request. A separate copy 
is not needed for Grants Management. Applicants unable to submit 
electronic applications should submit a complete written application 
addressed to the same NINDS contact.

Budget Information:   Supplements will be awarded as TOTAL COSTS, and 
are one-time awards. Any Facilities and Administrative (indirect) costs 
should be included in the modular request, and may not be added to it.  
For R01s, R21s, R29s, and R44s the maximum request is $50,000.  For 
P01s, P50s, and U54s the maximum is $100,000.  Although the awarded 
budgets will be modular, applicants should provide budget justification 
that details the budget items requested, including Facilities and 
Administrative (F&A) costs.

Review Procedures:  Requests will be reviewed administratively.  Review 
criteria will include the scientific significance to PD research, and 
relevance to program priorities of the institute. 

Post-Award Requirements: A short, 1-page progress report addressing the 
results of the supplement will be required as an addition to the 
subsequent progress report of the parent grant.

Receipt Date: February 7, 2001

Earliest Award Date:  May 1, 2001


A website with FAQ"s about the program has been provided at:

Direct inquiries regarding programmatic issues to: 

Dr. Diane D. Murphy
Program Director, Neurodegeneration Group
National Institute of Neurological Disorders and Stroke
6001 Executive Blvd. NSC Rm. 2223
Bethesda, MD  20892
Tel: (301) 496-5680
Fax: (301) 480-1080

Direct inquiries regarding application issues to:

Dr. Carlos Pena
Program Analyst, Neurodegeneration Group
National Institute of Neurological Disorders and Stroke
6001 Executive Blvd. NSC Rm. 2228
6001 Executive Blvd. NSC Rm. 2223
Bethesda, MD  20892
Tel: (301) 496-5680
Fax: (301) 480-1080

Direct inquiries regarding fiscal matters to: 

Dianna Jessee
Grants Management Branch
National Institute of Neurological Disorders and Stroke 
6001 Executive Blvd., NSC 3290 
Bethesda, Maryland 20892 
Tel: 301-496-9231 
Fax: 301-402-0219 

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
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9000 Rockville Pike
Bethesda, Maryland 20892
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