Notice of Intent to Publish a Funding Opportunity Announcement for Advancing Integrated Models (AIM) of Care to Improve Maternal Health Outcomes among Women Who Experience Persistent Disparities (R01 Clinical Trial Required)
Notice Number:

Key Dates

Release Date:
December 30, 2021
Estimated Publication Date of Funding Opportunity Announcement:
February 11, 2022
First Estimated Application Due Date:
April 07, 2022
Earliest Estimated Award Date:
September 01, 2022
Earliest Estimated Start Date:
September 01, 2022
Related Announcements


Issued by

National Institute of Nursing Research (NINR)

National Institute on Minority Health and Health Disparities (NIMHD)

Tribal Health Research Office (THRO)


The purpose of this notice is to inform the research community of the National Institute of Nursing Research (NINR) and above participating NIH Institutes, Centers, and Offices (ICOs) intent to publish a funding opportunity announcement, advancing integrated models (AIM) of care, to foster intervention research that addresses structural inequities and reduces disparities in severe maternal morbidity and mortality.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

This FOA will utilize the R01 activity code. Details of the planned FOA are provided below.

Research Initiative Details

Research Objectives
Persistent disparities in maternal health outcomes is a public health crisis that requires new insights and solutions. The AIM initiative seeks to advance the development, implementation, and evaluation of integrated models of supportive care to prevent adverse maternal health outcomes among disproportionately impacted populations (i. e., Black/African American, American Indian/Alaska Native, Native Hawaiian/Other Pacific Islander, Hispanic/Latina, and Asian women). In this initiative, integrated supportive care is defined as care that addresses healthcare access, healthcare quality, and the social conditions in which people live, work, worship, and play through use of supportive care persons and services (e.g., doula, community health worker, social service provider, patient navigation). Interventions can be implemented within any system of pregnancy care and delivery such as obstetric clinics, hospital-based care, or care provided through a birthing center. Studies must incorporate a conceptual framework and examine the mechanisms by which supportive care impacts severe maternal morbidity and/or mortality outcomes. Women should be recruited early in pregnancy, ideally during the antepartum period, and followed one-year postpartum. Maternal mortality and/or severe maternal morbidity is a required primary outcome. AIM interventions must target the following domains of interest: healthcare access, healthcare quality, and social conditions. Specific focus within each domain can include, but is not limited to:

  • Healthcare access related to appointment scheduling, care coordination, availability of care, and health insurance status;
  • Healthcare quality related to timeliness of care, comorbid diagnoses, provision of general and specialty care, labor and delivery support, patient-provider communication, and education; and
  • Social conditions related to food access, transportation, and housing.

Studies must involve the priority population of pregnant/postpartum women in the intervention research process. This can be accomplished through multisectoral partnerships with, but not limited to, patient advocacy groups, community-based organizations, obstetric clinics, hospital systems, social service organizations, birthing centers, and tribal communities and organizations.

Funding Information
Estimated Total Funding


Expected Number of Awards

4 awards

Estimated Award Ceiling

Application budgets are not limited but need to reflect the actual needs of the proposed project.

Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 


Please direct all inquiries to:

Shalanda A. Bynum, PhD, MPH

National Institute of Nursing Research (NINR)


Priscah Mujuru
National Institute on Minority Health and Health Disparities (NIMHD)

Juliana Blome, PhD, MPH
Tribal Health Research Office (THRO)