Key Dates
NOT-MH-23-335 - Notice of Intent to Publish a Funding Opportunity Announcement for Approaches to Identifying Preteen Suicide Risk and Protective Factors (R01 Clinical Trial Not Allowed)
National Institute of Mental Health (NIMH)
The National Institute of Mental Health (NIMH) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for a data coordinating center (DCC) in support of a research consortium of R01 foundational research projects (that will aim to refine and test valid methods for characterizing preteen suicide risk and protective factors across multiple domains, and for operationalizing suicidal thoughts and behavior (STBs) and non-suicidal self-injury (NSSI) among preteen youth (ages 8-12). Key DCC activities will include the coordination of data formatting and harmonization efforts across R01 Consortium sites to optimize sharing with the NIMH Data Archive (NDA), as well as coordinating data sharing timelines across R01 sites. Data combined by the DCC, and held within the NDA, will facilitate the harmonization of data related to risk and protective factors, NSSI, and STBs in preteen youth and promote analyses that leverage the power of combined cohorts.
This Notice of Intent to Publish (NOITP) is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects, and to consult with NIH to submit responsive applications.
The NOFO is expected to be published in Summer 2023, with an expected application due date in Fall 2023.
This NOFO will utilize the U24 activity code. Details of the planned NOFO are provided below.
Background
Suicide rates among youth in the United States are a significant public health concern. Youth and young adults ages 10 24 account for 14% of suicides. For youth ages 10-14, suicide is the second leading cause of death (see Disparities in Suicide). Although age-specific suicide rates for youth aged 10-14 are low relative to adults, suicide deaths in this age range tripled between 2007 and 2020, and girls aged 10-14 continued to have increasing rates during 2018-2020, a period when adult suicide deaths decreased (see Suicide Mortality in the United States, 2000-2020). In addition, trends in suicide death for children and adolescents show many of the same disparities for suicide deaths in other age groups. Sexual and gender minority, American Indian, and Alaska Native youth experience the highest rates of youth suicide (Disparities in Suicide). Moreover, the rate of suicide deaths over time has continued to trend upward for racial and ethnic minority youth, including those who identify as Black, Hispanic, Latine, Asian American, Native Hawaiian, and Pacific Islander.
To understand the concerning increases in suicide deaths among children and young adolescents and to understand why some groups are of greater risk, there is a clear need for preliminary work to refine approaches for sampling youth who are at increased risk for suicidal thoughts and behaviors, including sub-populations who experience elevated risk or health disparities, for characterizing risk/protective factors across multiple domains, and for operationalizing STBs and non-suicidal self-injury (NSSI) among preteen youth.
Scope and Objective
The Notice of Funding Opportunity (NOFO) is intented to support a data coordinating center (DCC) to facilitate collaborations across research projects funded under the companion NOFO, RFA-MH-24 -320.
The DCC is intended to conduct the following activities:
Leadership and Personnel Expertise
The PD/PI (or Multi-PDs/PIs) of the Coordinating Center should demonstrate leadership in data coordination in the context of trans-disciplinary research efforts, along with expertise in designing and implementing longitudinal studies relevant to the research projects. The team must have the experience to track progress and ensure the consistency of potential harmonized measures across independent research sites.
Potential applicants are strongly encouraged to consult with NIMH program staff when developing plans for an application.
Funding Information
TBD
1
TBD
93.242
Applications are not being solicited at this time.
Inquiries
Please direct all inquiries to:
Eric R. Murphy, Ph.D.
National Institute of Mental Health (NIMH)
Telephone: 301-443-9230
Email:eric.murphy@nih.gov