November 19, 2021
PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
National Institute of Mental Health (NIMH)
National Eye Institute (NEI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute on Drug Abuse (NIDA)
National Institute of Neurological Disorders and Stroke (NINDS)
National Center for Complementary and Integrative Health (NCCIH)
The purpose of this Notice of Special Interest (NOSI) is to announce the availability of administrative supplements to integrate neuroethics perspectives and approaches into existing BRAIN Initiative supported research.
The Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to identify, treat, cure, and even prevent brain disorders.
As one of several federal agencies involved in the BRAIN Initiative, NIH's contributions to the BRAIN initiative were initially guided by "BRAIN 2025: A Scientific Vision," a strategic plan that detailed seven high-priority research areas. This plan was updated and enhanced in 2019 by: "The BRAIN Initiative 2.0: From Cells to Circuits, Toward Cures" and "The BRAIN Initiative and Neuroethics: Enabling and Enhancing Neuroscience Advances for Society."
The NIH encourages BRAIN Initiative applications from groups that are underrepresented in the biomedical, behavioral, or clinical research workforce (see data at http://www.nsf.gov/statistics and the most recent report on Women, Minorities, and Persons with Disabilities in Science and Engineering). Such individuals include those from underrepresented racial and ethnic groups, those with disabilities, and those from disadvantaged backgrounds.
Supplement applications are encouraged from currently funded BRAIN Initiative projects that can readily incorporate core ethical questions associated with research focused on the human brain related to emerging technologies and advancements in research supported by the BRAIN Initiative. The goal of this NOSI is to accelerate the scientific impact of the BRAIN Initiative grants by supporting activities that advance the aims by integrating a grounded neuroethics perspective to the funded project. The intent is that efforts supported through this administrative supplement would be both complementary to and integrative with the transformative, breakthrough neuroscience discoveries supported through the BRAIN Initiative. The requested supplemental component(s) must be within the scope of the original aims.
Examples of relevant activities that integrate neuroethics perspectives may include but are not limited to:
Research Participant Engagement, Special Populations, and Social Implications
Data collection/storage/sharing and model systems
In each case, the work proposed should advance the aims and be feasible to complete within a one-year timeframe with the funds permitted (see below). Investigators should also consider whether their proposed project might be suitable for independent support through the BRAIN Initiative Neuroethics RFA-MH-21-205.
Description of circumstances for which administrative supplements are available.
Application and Submission Information
Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.