Notice Number: NOT-MH-19-004
Release Date: November 21, 2018
National Institute of Mental Health (NIMH)
The National Institute of Mental Health (NIMH) announces the opportunity for investigators with relevant active NIMH-supported research including but not limited to research project grants (R01, R03, R15, R21, R61/33, R21/33, R33, R34, and R37), research centers (P-grants) and cooperative agreements (U-grants) to submit administrative supplements according to PA-18-591 and its reissues, Administrative Supplements to Existing NIH Grants and Cooperative Agreements(Parent Admin Supp Clinical Trial Optional), for funded projects that could benefit from: (1) explanatory computational models (theory- and/or data-driven) to test underlying brain and behavioral mechanisms; and (2) analytical approaches leveraging complex datasets within and across levels of analysis (e.g., genes, molecules, cells, circuits, physiology, and behavior).
This Notice will support the implementation of computational, theoretical, and analytical approaches in existing basic, translational, clinical neuroscience and neuropsychiatry, and mental health intervention and services research grants. The intent of these supplements is to support the addition of computational approaches for interpreting mental health-relevant data. Applicants for the administrative supplements are encouraged to form new collaborations between computational modelers, clinicians, neuroscientists, biologists, biostatisticians, mathematicians, engineers, geneticists, etc. as such, funds should be used to pay for effort of computational modeler or addition of post-doc; to pay for computational resources/equipment necessary for building/testing models related to already acquired clinical data-sets; for something directly related to time/effort needed to design new pilot experiments. Administrative supplements must add value to the science proposed in the aims of the original project, as such they must be within the scientific scope of the parent grant.
In general, NIMH is interested in integrating: deep-learning algorithms with effective explanatory techniques; theory-driven models with data-driven models; bottom-up models with top-down models; and in multi-modal data fusion algorithms (e.g., multi-kernel learning) to mechanistically link distinct levels of analysis to one or multiple outcome measures. Examples of the types of supplements that are of interest include, but are not limited to the following:
These administrative supplements are available to meet increased costs that are within the scope of the approved award, but were unforeseen when the new or renewal application or grant progress report for non-competing continuation support was submitted.Applications for administrative supplements are considered prior approval requests (as described in Section 220.127.116.11 of the NIH Grants Policy Statement) and will be routed directly to the Grants Management Officer of the parent award. There is no guarantee that funds are available from NIMH or for any specific grant. All applicants are encouraged to discuss potential requests with their program official. Additionally, prior to submission, applicants must review NIHM's web site to ensure they meet the IC's requirements.
Budget and Available Funds
Supplement budgets are limited to one year and may not exceed $100,000 in direct costs (including costs for all applications combined in a collaborative set), and are expected to reflect actual needs of the proposed project.
Projects well-aligned with this Notice but requiring larger budgets (and/or longer time frames) or an expansion of the project’s approved scope or research protocol may submit a Revision Application (formerly termed Competitive Supplement). Revision applications are submitted using the forms, instructions, and guidelines detailed in the parent grant’s originating FOA. Should the parent grant’s FOA be expired, applicants are encouraged to apply via the guidelines for the appropriate parent or omnibus announcement.
NIMH intends to commit approximately $1 million in direct cost in FY19 to support approximately 10 administrative supplements. Future year amounts will depend on annual appropriations.
Submitting an Application
Applicants should begin their application by stating: “This application is being submitted in response to NOT-MH-19-XXX". For additional reference, see the parent program announcementto Administrative Supplements to Existing NIH Grants and Cooperative Agreements(Parent Admin Supp Clinical Trial Optional) PA-18-591.
Applications are due by 5:00 PM local time on April 1 of each year.
Please direct all inquiries to:
Michele Ferrante, PhD
National Institute of Mental Health (NIMH)