Notice Number: NOT-MH-17-009

Key Dates
Release Date: January 25, 2017

NOT-MH-25-055, Notice Announcing the National Institute of Mental Health (NIMH) Expectations for Collection of Common Data Elements.

Issued by
National Institute of Mental Health (NIMH)

Purpose

The purpose of this Notice is to extend the data-harmonization effort at the National Institute of Mental Health (NIMH) announced in NOT-MH-15-009.

One way to improve the yield and impact of research in any area of science is to provide investigators with a common set of tools and resources to facilitate sharing, comparing, and integration of data from multiple sources. NIMH has already made a significant investment in a data repository to hold human subjects data related to mental illness and related fields. This repository allows data from multiple sources to be aggregated and easily accessed by the research community. However, the data repository is most useful when research laboratories collect data using the same set of data elements.

With this Notice, NIMH announces the availability of a set of data elements related to early psychosis. One collection of translational research measures is intended for use by scientists who are collecting data from human subjects in the early stages of psychotic illness. A second collection of clinical service measures is proposed for use in community clinics offering specialty treatment related to early psychosis. The new collections of common data elements are available via the PhenX Toolkit. NIMH grantees/applicants are strongly encouraged to incorporate these measures into research protocols and are discouraged from using alternative measures to collect similar data. By encouraging the use of this set of data elements, NIMH is trying to promote these into the category of common data elements widely used by a research field.

NIMH recognizes that researchers may have longstanding data collection protocols that do not incorporate the recommended measures. In such situations, it may be necessary to collect data using more than one measure to ensure compatibility with legacy data as well as to allow data from multiple laboratories to be easily aggregated as the field moves forward. Researchers may also want to include additional measures of a construct to best address their hypotheses. This Notice does not preclude the use of measures in addition to the common data elements that have been established.

In order to allow investigators to prepare to administer new instruments and to budget appropriately, NIMH expects that applications submitted for funding after June 1, 2017 will incorporate these measures in all research proposed that involves human participants. Current NIMH awardees are invited to talk to their Program Officer about the possibility of an administrative supplement to allow common data elements to be collected in ongoing studies.

Through the use of these measures, NIMH-funded researchers will be better able to share, compare, replicate findings, and integrate data across studies. By advocating the use of these common measures and aggregating the data in the repositories listed above, NIMH aims to optimize the value of this research and further accelerate and enhance our understanding of mental illness, while advancing a culture of scientific collaboration.

Inquiries

Please direct all inquiries to:

Gregory K. Farber, Ph.D.
National Institute of Mental Health
Telephone: 301-435-0778
Email: [email protected]