NOT-MH-10-017: Notice of Intent to Publish a Funding Opportunity Announcement for the Novel NeuroAIDS Therapeutics: Integrated Preclinical/Clinical Program award (P01)

Notice of Intent to Publish a Funding Opportunity Announcement for the Novel NeuroAIDS Therapeutics: Integrated Preclinical/Clinical Program award (P01)

Notice Number: NOT-MH-10-017

Key Dates
Release Date: May 24, 2010

Issued by
National Institute of Mental Health (NIMH) (http://www.nimh.nih.gov)

Purpose

The National Institute of Mental Health (NIMH) intends to issue a Funding Opportunity Announcement (FOA) for the following award: Novel NeuroAIDS Therapeutics: Integrated Preclinical/Clinical Program (P01). This award seeks to support studies focused on accelerating basic and translational scientific discoveries with a plan to advance drug therapeutics for HIV-Associated Neurocognitive Disorders (HAND). Recent clinical observations indicate that over 50% of HIV infected patients manifest HAND despite receiving highly active antiretroviral therapy (HAART). These clinical observations inform the need to obtain a better understanding of HAND and to develop novel therapeutic drug candidates to prevent or interfere with progression of HAND. Applicants are invited to develop a multidisciplinary program with a minimum of three highly integrated research projects and one Administrative Core focused on research and development of novel therapeutics for HAND. At least one component (research project) may be derived from industry (i.e., pharmaceutical, chemical, bioengineering or biotechnological companies). A Scientific Advisory Panel (SAP) for each award under this FOA will be constituted within 6 months of the award.

This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in the summer of 2010.

This FOA will utilize the P01 mechanism. Projects with a proposed clinical component will be converted to a cooperative agreement U19 when the program transitions to a clinical mode.

APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.

Inquiries

Interested parties may contact:

Jeymohan Joseph, Ph.D.
Division of AIDS Research
National Institute of Mental Health
6001 Executive Boulevard, Room 6219, MSC 9619
Rockville, MD 20892-9619
Telephone: (301) 443-6100
Email: [email protected]