Notice of Intent to Publish a Funding Opportunity Announcement for Research to Advance the Science of Primary Care (R01)
Notice Number:

Key Dates

Release Date:
March 15, 2024
Estimated Publication Date of Notice of Funding Opportunity :

Spring 2024

First Estimated Application Due Date:

Summer 2024

Earliest Estimated Award Date:


Earliest Estimated Start Date:


Related Announcements
  • March 29, 2024 - Research to Advance the Science of Primary Care (R01). See Notice PA-24-205
  • January 26, 2023 - AHRQ Small Research Projects to Advance the Science of Primary Care (R03). See NOFO PA-23-115
  • March 17, 2022 - AHRQ Announces Interest in Primary Care Research. See NOT-HS-22-011
Issued by



The Agency for Healthcare Research and Quality's (AHRQ) mission is to produce evidence to make healthcare safer, higher quality, more accessible, equitable, and affordable. AHRQ works within the U.S. Department of Health and Human Services (HHS) and with other partners to ensure that the evidence is understood and used.  

AHRQ intends to publish a Notice of Funding Opportunity (NOFO) to invite applications to support expanding research and evidence in primary care. Primary care research is research conducted for the purpose of better understanding or improving primary care; specifically, it is research that is a) conducted in a primary care setting, b) about primary care patients, clinicians, or teams, or c) on a topic that is integral to, or has direct implications for, the delivery of primary care.  

AHRQ is interested in applications to build evidence about the characteristics and value of primary care that influence patient outcomes and advance health equity, such as care coordination, continuity of care, comprehensiveness of care, person-centered whole healthcare, and trust. AHRQ is interested in research that explores how these can be improved, measured, and effectively delivered to strengthen primary care across the lifespan (including perinatal care, pediatric and adolescent health, transition from pediatric to adult care, sexual and reproductive health, women's health, and care of older adults).  This includes a focus on clinical preventive services, and prevention and management of multiple chronic conditions. AHRQ is especially interested in how these characteristics of primary care can be applied to address challenges facing primary care, such as workforce shortages, health disparities, fragmentation, partnership with communities, human services, and public health, and shifting practice organization and ownership.  

The NOFO will prioritize research that aims to improve primary care in terms of quality, safety, access, affordability, and equity, which may include attention to the primary care workforce, patient experience or outcomes, social determinants of health, care delivery models, payment, or digital healthcare. The research strategy proposed by applicants must be related to the mission and research interests of AHRQ and its National Center for Excellence in Primary Care Research (NCEPCR). 

This Notice encourages investigators with appropriate expertise and capabilities to begin to consider applying for the upcoming NOFO. AHRQ intends to publish the NOFO in Spring 2024.  

Funding Information

Estimated Total Funding


Expected Number of Awards
Estimated Award Ceiling


Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization

Applications are not being solicited at this time. 


Please direct all inquiries to:

Aimee R. Eden, PhD, MPH 
Acting Director, National Center for Excellence in Primary Care Research 
Center for Evidence and Practice Improvement 
Agency for Healthcare Research and Quality