Notice of Intent to Publish Funding Opportunity Announcements (FOAs) to Disseminate and Implement Patient-Centered Outcomes Research Findings through Clinical Decision Support (U18 and R18)

Notice Number: NOT-HS-15-010

Key Dates
Release Date: July 9, 2015

Related Announcements
This Notice supersedes AHRQ Notice NOT-HS-15-002, released November 3, 2014.

Issued by
Agency for Healthcare Research and Quality (


AHRQ intends to launch a new initiative to disseminate and to implement patient-centered outcomes research (PCOR) findings through clinical decision support (CDS). This initiative includes planning for three funding opportunity announcements (FOAs). Together, the three FOAs focus on (1) creating a PCOR CDS Learning Network to drive the field of CDS forward and on conducting CDS projects to (2) extend existing or (3) develop new CDS based on PCOR findings.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The planned FOAs are expected to be published in 2015 and continue into 2016. The FOAs will utilize the U18 and R18 activity codes. Details of the planned FOAs are provided below.

Research Initiative Details

The Patient Protection and Affordable Care Act (ACA) of 2010 directs AHRQ to disseminate and to build capacity in the area of PCOR ( AHRQ has specific requirements related to dissemination of PCOR findings and CDS. Working with relevant medical and clinical associations, AHRQ is to assist users of health IT focused on CDS to incorporate PCOR findings into clinical practice and to promote the ease of use of such incorporation. In addition, AHRQ is to establish a process to receive feedback from stakeholders about the value of the information disseminated and assistance provided.

To address this directive, AHRQ intends to launch a PCOR CDS initiative that fulfills these requirements using both grant and contract mechanisms. In addition to promoting the dissemination and implementation of PCOR findings, the goals of the initiative are to develop and spread CDS based on PCOR findings and to develop tools to help CDS artifacts become more shareable, health IT standards-based, and publicly-available. Plans for the PCOR CDS initiative include the following components:

  1. Engage stakeholders to catalyze the development and use of PCOR-based CDS throughout the health care system and provide CDS developers and stakeholders with constructive advice and feedback;
  2. Develop and test resources ( artifacts ) for CDS implementation based on PCOR findings, including coded clinical knowledge and implementation guides;
  3. Develop a publically accessible repository of PCOR findings suitable for CDS development and the infrastructure for sharing PCOR-based CDS; and
  4. Evaluate the overall initiative.

AHRQ is planning three FOAs that will separately solicit applications for the following:

  1. Creating the AHRQ PCOR CDS Learning Network. The PCOR CDS Learning Network will build a community of stakeholders, including clinicians, patients, professional associations, health IT developers, and others, aimed at disseminating and incorporating PCOR findings in clinical practice through CDS. The planned FOA will use the U18 activity code.
  2. Extending ("scaling") existing, well-established CDS beyond the initial setting or institution in which the CDS was developed to disseminate and implement PCOR findings. The planned FOA will use the R18 activity code.
  3. Developing new, reliable, valid, and usable CDS from PCOR findings and demonstrating its effectiveness to improve care in clinical practice. The planned FOA will use the R18 activity code.

AHRQ plans to strongly encourage collaboration between the PCOR CDS Learning Network and awardees under the R18 FOAs.



Please direct all inquiries to:
Amy Lindinha
Agency for Healthcare Research and Quality (AHRQ)