Notice of Intent to Publish a Funding Opportunity Announcement for Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR)

Notice Number: NOT-HL-18-632

Key Dates
Release Date: June 29, 2018

Estimated Publication Date of Funding Opportunity Announcement: 10/03/2018
First Estimated Application Due Date: 02/08/2019
Earliest Estimated Award Date: 10/29/2019
Earliest Estimated Start Date: 11/29/2019

Related Announcements

Issued by
National Heart, Lung, and Blood Institute (NHLBI)


The National Heart, Lung and Blood Institute (NHLBI) intends to publish a new Funding Opportunity Announcement (FOA) to invite applications that propose to test strategies for delivering proven-effective, evidence-based, community-level interventions for reducing or eliminating cardiovascular and/or pulmonary health disparities, and that promote and improve population health in high-burden communities.

In the face of persistent and often widening disparities in cardiovascular and pulmonary health, disease, and risk factors, a large number of proven-effective interventions that can improve health outcomes exists. This initiative will seek applications that propose to utilize these known interventions to determine optimal and sustainable delivery strategies that provide generalizable knowledge for reducing or eliminating disparities in cardiovascular and pulmonary health, disease, and risk factors in high burden communities across the U.S.

The NHLBI is interested in applications that will address questions relevant to the NHLBI mission and align with the Institute's Strategic Vision ( ).

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in Fall 2018 with an expected application due date in Winter 2019.

This FOA will utilize the UG3/UH3 activity code, a bi-phasic, milestone-driven cooperative agreement. The NHLBI also intends to support a Data Coordinating Center to provide support and coordination for the awardees funded through the UG3/UH3 FOA to provide organizational infrastructure for collaboration, facilitate data harmonization and standardization, optimize data sharing, and facilitate implementation science innovation and skills building across awardees. Details of the planned FOA are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insight in the areas of cardiovascular and pulmonary health disparities; implementation science; community-engaged and/or community-based participatory research; and/or health services and multilevel, multicomponent intervention delivery science to consider applying to this new FOA.

Applications that propose collaborative approaches by investigators with combined expertise in behavioral, clinical and social sciences, implementation science, health disparities, economics, epidemiology, and/or policy are also encouraged.

The NHLBI anticipates that proposed projects will employ proven-effective community-engaged, community-based participatory approaches to address disparities within communities that have well-documented, high burdens of cardiovascular and/or pulmonary diseases and health risk factors. Awards supported by this initiative will utilize strategies to enhance evidence-based intervention adoption, fidelity, and sustainability. The NHLBI anticipates that applications will:

  • Propose a multilevel, multicomponent Hybrid Type III implementation research design to determine optimal and sustainable delivery strategies for the combination of at least three proven-effective interventions to address cardiovascular and/or pulmonary disease risk factors, as well as inform understanding of key mediators/mechanisms for adoption, implementation, and sustainability;

  • Propose community-based participatory partnerships that include one or more research institutions and key community stakeholders, particularly stakeholders with access to and knowledge of high burden populations, but whom have traditionally lacked financial or human capital resources, and/or research infrastructure;

  • Include assessment of implementation costs as an integral part of the proposed project;

  • Utilize a validated implementation research framework (e.g., REACH, CFIR, RE-AIM, PRECEDE-PROCEED);

  • Include linkages to healthcare delivery within the community (e.g., primary care, community health workers, federally-qualified health centers, etc.);

  • Leverage existing and/or previous efforts to address health disparities (e.g., Million Hearts, Evidence Now, CDC Racial and Ethnic Approaches to Community Health (REACH), etc.), and previous NIH-funded research (e.g., SPRINT, DASH diet, etc.);

  • Include a core group of measures related to disparities burden (e.g., population-level lifetime cardiovascular risk; risk of developing chronic obstructive pulmonary disease (COPD); geo-spatial profiles of community disease burden; community indicators of the social determinants of health; predicted and/or currently observed regional mortality rates; CDC community health status indicators);

  • Focus on at least one community with a high burden of cardiovascular and/or pulmonary health disparities (e.g., geographic region, rural or inner-city locale, racial/ethnic group, socioeconomic status, sex);

  • Engage early stage investigators within research teams to increase the cadre of researchers with skills in community-engaged implementation research who are capable of addressing cardiovascular and/or pulmonary health disparities.

It is anticipated that as a group, FOA awardees will constitute a collaborative network with capabilities for addressing research questions aimed at reducing or eliminating disparities and improving health outcomes in cardiovascular and pulmonary disease within the U.S. population.

Funding Information
Estimated Total Funding: $8,625,000 total costs
Expected Number of Awards: 9
Estimated Award Ceiling: $850,000 total costs
Primary CFDA Numbers: 93.840

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
City or township governments
Special district governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization

Applications are not being solicited at this time.


Please direct all inquiries to:

Melissa C. Green Parker, Ph.D.
National Heart, Lung, and Blood Institute (NHLBI)

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