RFP Announcement: Jackson Heart Study Renewal - Coordinating Center, Community Engagement Center, and Training and Education Center

Notice Number: NOT-HL-17-544

Key Dates
Release Date: October 12, 2017

Related Announcements
NOT-HL-17-552
NOT-HL-17-553
NOT-HL-17-554
NOT-HL-17-555
NOT-HL-17-556

Issued by
National Heart, Lung, and Blood Institute (NHLBI)

Purpose

As part of the Jackson Heart Study renewal, the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), plans to solicit proposals from qualified organizations to establish one (1) Coordinating Center; one (1) Community Engagement Center; and up to two (2) Training and Education Centers. The RFPs can be accessed through the FedBizOpps (https://www.fbo.gov/) via the following Solicitation Numbers:  HHSN26818HV00006R, HHSN26818HV00008R, and HHSN26818HV00009R The electronic RFPs contain all information needed to submit a proposal.

An RFP Announcement will be published in the near future regarding NHLBI's plans to solicit proposals for one (1) Field Center.  

Research Initiative Details

The Jackson Heart Study (JHS), initiated in 1998, is a longitudinal investigation of genetic and environmental risk factors associated with the disproportionate burden of cardiovascular disease (CVD) in African-Americans. In addition, the JHS performs a variety of community education and outreach activities to promote healthy lifestyles and reduce disease risk burden. It also conducts college undergraduate and graduate-level training programs and high school science and math enrichment programs to prepare and encourage underrepresented minority students to pursue biomedical careers (www.jacksonheartstudy.org/).

The study recruited 5306 African-American residents living in the Jackson, MS, metropolitan area of Hinds, Madison, and Rankin Counties. Enrolled JHS participants, initially aged 20 - 90 years, received three back-to-back examinations (Exam 1, 2000-04; Exam 2, 2005-08; and Exam 3, 2009-13).  Participant exams have produced extensive longitudinal data on traditional and putative CVD risk factors, socioeconomic and sociocultural factors, and biochemical analytes; and measures of subclinical disease from echocardiography, cardiac magnetic resonance imaging, and computed tomography scans of the heart, aorta, and abdomen. Stored biological samples and DNA are available.  Participants are contacted annually and ascertainment of incident clinical CVD events of interest is ongoing. 

The JHS renewal will continue novel epidemiologic research on cardiovascular and related diseases in this cohort, serve as a resource to the scientific community for future research and as a platform for in-depth ancillary studies, promote cardiovascular health in the local community, and encourage underrepresented minority students to pursue biomedical careers. The JHS centers will include:

  1. A Coordinating Center to maximize use of data and samples amassed in JHS over 16 years to address new questions about the development and progression of clinical CVD and related conditions.
  2. A Field Center to continue contact with and data collection in the JHS cohort to address new questions about the development and progression of clinical CVD and related conditions.
  3. A Community Engagement Center to support activities to promote cardiovascular health in the Jackson community and beyond. 
  4. Up to two (2) Training and Education Centers for cardiovascular epidemiology and related biomedical research, targeting underrepresented minority undergraduate and/or post-graduate students and leveraging the resources and research opportunities of the JHS.

Potential offerors are responsible for downloading the RFP and any attachments. It is also the offeror's responsibility to monitor the FedBizOpps web page (https://www.fbo.gov/) for the release of any amendments to the RFP. Interested parties must respond to the solicitation in order to be considered for award of any resultant contract. This acquisition has been designated as a full and open competition under the North American Industry Classification System (NAICS) code 541712. Subcontracting opportunities are anticipated during the course of these contract awards.

Awards for the JHS are anticipated to be made on or about August 15, 2018.

Inquiries

Please direct all Coordinating Center and Training and Education Center inquiries to:

Pam McCord-Reynolds
National Heart Lung, and Blood Institute (NHLBI)
Telephone: 301-827-7538
Email: mccordreynoldp@nhlbi.nih.gov

Please direct all Field Center and Community Engagement Center inquiries to:

Mark Brady
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: 301-827-7532
Email: mark.brady@nih.gov