Notice of Intent to Publish a Funding Opportunity Announcement for ImPlementation REsearCh to DEvelop interventions for People Living with HIV (PRECluDE) (U01)

Notice Number: NOT-HL-16-444

Key Dates
Release Date:  September 13, 2016

Estimated Publication Date of Announcement: Winter 2016
First Estimated Application Due Date: Spring 2017
Earliest Estimated Award Date: Fall 2017
Earliest Estimated Start Date: Fall 2017

Related Announcements
RFA-HL-18-007

Issued by
National Heart, Lung, and Blood Institute (NHLBI)

Purpose

The National Heart, Lung, and Blood Institute intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for research on implementation research in the delivery of proven effective interventions for comorbid heart, lung, blood, and sleep (HLBS) diseases and conditions in people living with HIV/AIDS (PLWHIV) domestically. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in Winter 2016 with intended application due dates in Spring and Winter 2017.

This FOA will utilize the U01 activity code. Details of the planned FOA are provided below.

Research Initiative Details

The intended FOA will solicit applications that propose late stage translation research in the delivery of proven effective interventions for comorbid HLBS diseases and conditions in PLWHIV domestically. This initiative will support collaborative research teams composed of multidisciplinary partners, (e.g. public health researchers, policy makers, academic and health system delivery researchers, community collaborators  and others) to conduct locally or regionally identified high priority late stage translation research focused on addressing HLBS comorbid diseases and conditions for PLWHIV in the U.S. For this FOA, implementation research in real world settings for the prevention, treatment, and control of HLBS diseases and conditions in PLWHIV using proven effective interventions will be encouraged.

The main objective of this initiative is to utlize implementation research models and strategies to address barriers that impede the scale-up and efficient application of proven effective interventions in community and clinical settings for the prevention, control, and treatment of comorbid HLBS conditions in PLWHIV. The focus is on implementation science within the late stage translation research (T4) phase which is defined as research that identifies implementation strategies to enhance sustainable uptake of proven effective interventions into “real world” settings.  Research outcomes include acceptability, affordability, and appropriateness of interventions as well as cost, feasibility, fidelity, penetration, and sustainability of the intervention in the specific context.

Applicants are encouraged, but not required to use a multiple program director/principal investigator (PD/PI) mechanism to facilitate collaborations between HIV, HLB implementation science investigators and community collaborators. Multidisciplinary teams and diverse areas of expertise may be represented. 

APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.

Inquiries

Please direct all inquiries to:

Cheryl Anne Boyce, Ph.D.
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: (301) 496-1051
Email: cheryl.boyce@nih.gov