Notice Announcing Updates to NHLBI Topics of Special Interest (TOSI)

Notice Number: NOT-HL-14-236

Key Dates
Release Date: September 4, 2014

Related Announcements

Issued by
National Heart, Lung, and Blood Institute (NHLBI)


NHLBI announces updated Topics of Special Interest (TOSI) that are of high programmatic interest. TOSI listing may be accessed at TOSI will change periodically as Institute programmatic interests dictate. These topics are not formal announcements for applications (Funding Opportunity Announcements). Although funds are not set aside for awards on these topics, applications submitted in response to TOSI are eligible for special funding consideration. TOSI applications will be peer reviewed by standing study sections at the NIH Center for Scientific Review (CSR).

Investigators interested in developing applications for these topics are encouraged to discuss their ideas with NHLBI contacts listed below. Researchers should submit investigator-initiated R01 applications through PA-13-302.

Updated TOSI:

  • HL-141: Primary Prevention Trials for Chronic Lung Diseases (R01)
  • HL-142: Exosomes as Paracrine Signal Mediators in Cardiovascular, Lung, and Blood Disease (R01)


Please direct all inquiries to:

For questions on HL-141
Patricia Noel, Ph.D.
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: 301-435-0202

Carol Blaisdell, M.D.
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: 301-435-0222

For questions on HL-142
Pothur Srinivas, PhD, MPH
National Heart, Lung, and Blood Institute (NHLBI)
Telephone: 301-402-3712