Release Date: August 22, 2012
National Heart, Lung, and Blood Institute (NHLBI)
As part of the Jackson Heart Study (JHS) renewal, the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), plans to solicit proposals from qualified organizations to establish:
* one (1) Field Center
* one (1) Community Outreach Center
* up to two (2) Training and Education Centers
* one (1) Coordinating Center
The RFPs can be accessed through the FedBizOpps (URL: https://www.fbo.gov/) or through the NHLBI website at the following address: URL: http://www.nhlbi.nih.gov/funding/inits/index.htm#rfp. The electronic RFPs contain all information needed to submit a proposal.
Research Initiative Details
The JHS is a multi-center investigation of predictors of
cardiovascular disease (CVD) in 5,301 African-Americans living in Hinds,
Madison, and Rankin Counties surrounding the Jackson, MS metropolitan area. The
JHS was initiated in 1998 as a collaborative effort among three Jackson-area
academic institutions. At the close of the current contracts in May 2013, the
JHS will have completed three back-to-back cohort examinations that have
produced extensive longitudinal data on traditional and putative CVD risk
factors, socioeconomic and sociocultural factors and biochemical analyses;
measures of subclinical disease from echocardiography, cardiac magnetic
resonance imaging (MRI), computed tomography (CT) scans of the heart, aorta and
abdomen; and stored biological samples. Eighty-two percent of the surviving JHS
participants (N = 4,203) completed Exam 2; projected retention for Exam 3 is
80% (N = 4,082). In addition, the JHS has conducted annual cohort follow-up
contacts for incident clinical events of interest, a variety of community
education and outreach activities to promote healthy lifestyles to reduce
disease risk burden, and level-appropriate academic training programs to
promote and support public health research.
The objectives of the renewal of the JHS program are to:
1) Support dedicated time for JHS investigators to conduct data analysis and prepare manuscripts using the wealth of data collected.
2) Facilitate access to study resources and expertise in order to:
- Engage researchers beyond the JHS, including early career investigators, in collaborative analysis of existing data to produce high quality publications.
- Serve as a training ground for undergraduate and graduate students to help ameliorate the shortage of minority biomedical researchers.
- Serve as a platform for ancillary studies.
3) Conduct annual phone interviews with participants to
identify interim hospitalizations and outpatient medical visits, convey
information about the JHS, and serve as a vehicle to recruit for ancillary
studies.
4) Continue clinical events identification, investigation,
and validation to improve statistical power for risk prediction and hypothesis
testing.
5) Perform community health education activities to disseminate health promotion and prevention messages in the Jackson community.
Potential offerors are responsible for downloading the RFP and any attachments. It is also the offerors' responsibility to monitor the FedBizOpps web page for the release of any amendments to the RFP. Interested parties must respond to the solicitation in order to be considered for award of any resultant contract. This acquisition has been designated as a full and open competition under the North American Industry Classification System (NAICS) code 541712. Subcontracting opportunities are anticipated during the course of this contract award.
Awards for the JHS are anticipated to be made on or about June 1, 2013.
Please direct all Community Outreach Center and Training and
Education Center inquiries to:
Catherine VanCise, Contracting Officer
National Heart Lung, and Blood Institute
301-435-0348
catherine.vancise@nhlbi.nih.gov
Please direct all Coordinating Center and Field Center inquiries to:
Austin Sachs, Contract Specialist
National Heart, Lung, and Blood Institute
301-435-0345
sachsa@nhlbi.nih.gov
and Human Services (HHS)
