Notice of Intent to Publish a Request for Applications for The Pediatric Heart Network (U10)

Notice Number: NOT-HL-11-104

Key Dates
Release Date:  March 5, 2010

Issued by
National Heart, Lung, and Blood Institute (NHLBI) (



The National Heart, Lung, and Blood Institute (NHLBI) and the Canadian Institutes of Health Research (CIHR) intend to issue a new Funding Opportunity Announcement (FOA) to solicit invitations to participate in the Pediatric Heart Network (PHN), a cooperative network of pediatric cardiovascular clinical research centers. 

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.  The FOA is expected to be published in June 2010 with an expected receipt date in October 2010.

The FOA will utilize the U10 mechanism.  Details of the planned FOA are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insights into clinical pediatric cardiovascular research and study conduct to begin to consider applying for the new FOA. 

The objectives of the PHN are to provide an infrastructure for multi-center collaborative clinical research; to evaluate medical, interventional, and surgical therapies; and to serve as a clinical trials training ground for fellows, junior faculty and research nurses.  The results of Network studies are expected to be widely disseminated and to improve the scientific basis of care for affected individuals.

The emphasis will be on clinical studies of approximately 24-36 months in duration that will help to identify optimal therapies. A limited number of clinical trials of longer duration may be considered. The knowledge gained is expected to advance the development and application of novel therapies and treatment approaches.

Equipping pediatric cardiovascular researchers with the skills and experience needed to conduct multi-center clinical trials is essential to carry out the aims of the PHN.  Funds for clinical research training have been included in this program.  How the funds are used will be determined by the PHN leadership shortly after the start of funding under this FOA. 



Interested parties may contact:

Gail Pearson, M.D., Sc.D.
Division of Heart and Vascular Sciences
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Room 8104
Bethesda, MD 20892-7940
Telephone: (301) 435-0510

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

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