Notice of the NHLBI Program in Computational Modeling for Heart, Lung, Blood, and Sleep Biologists: Introductory Courses

Notice Number: NOT-HL-06-115

Key Dates
Release Date: January 31, 2006

Issued by
National Heart, Lung, and Blood Institute (NHLBI), (

The purpose of this Notice is to announce the intention to issue a Request for Applications (RFA) in early 2006 to support development, implementation, and evaluation of one week short courses to introduce computational modeling approaches to biomedical researchers and clinician-scientists. The receipt date for applications would be in the late spring of 2006.

This RFA will support innovative strategies to promote interdisciplinary research and training by increasing the number of researchers with knowledge and skills to apply both experimental and computational approaches to heart, lung, blood, and sleep (HLBS) research. The HLBS systems involve multiple interacting networks over a wide range of physical and temporal scales, making them excellent candidates for computational modeling. Participants in these three distinct one-week courses, each offered twice a year, will learn to use computational tools, discover how these tools can complement experimental approaches, and apply computational models to specific research issues. The courses may also include an optional second phase of mentorship focused on applying computational modeling to the participant's research, which would reinforce and put into practical use the training received in the short course.

The experience generated by this effort will contribute to the development of heuristically accurate physiological models of the underlying pathways to disease, the interaction of disease components with each other and with the environment.  Results have the potential to identify novel predictors of disease, new therapeutic interventions, prevention strategies and treatments, as well as predictors of response to treatment.  

This Notice is to encourage investigators who believe that they have sufficient expertise to begin considering applying for this RFA program.


Interested parties may contact:

Jennie E. Larkin, Ph.D.
Division of Heart and Vascular Disease
National Institutes of Health
6701 Rockledge Drive
Room 9142, MSC 7940
Bethesda , MD 20892-7934
Telephone: (301) 435-0513
FAX: (301) 480-1335


Pothur Srinivas, Ph.D., MPH
Division of Heart and Vascular Disease
National Institutes of Health
6701 Rockledge Drive
Room 10188, MSC 10193
Bethesda , MD 20892 - 7956
Telephone: (301) 435-0550
FAX: (301) 480-2858

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