RELEASE DATE:  June 22, 2004


National Heart, Lung, and Blood Institute (NHLBI)


The NHLBI is requesting competing renewal applications from the investigators 
currently funded as part of the NHLBI Family Blood Pressure Program (please see for currently funded 
applications).  These programs were awarded as a result of Request for 
Applications (RFA) HL-94-011, Genetic Determinants of High Blood Pressure 
( and its 
competing renewal.  This Program consists of four Networks investigating the 
genetic contributions to hypertension and associated risk factors.  The FBPP 
provides a unique collaborative structure for basic and clinical research in 
hypertension. The extensive time and processes involved in establishing a 
collaboration essential for efficient development and implementation of protocols 
and analysis as a Program warrants this limited re-competition for one three year 
renewal cycle.  The experience gained by the current group of investigators in 
working together, designing protocols suitable for a research network setting, 
standardized quality control and producing high quality follow-up data is 
considerable.  The FBPP pooled data set provides a unique resource of unparalleled 
value for hypertension gene discovery and studies of complex disease genetics.  
The NHLBI would like to provide continued support to the FBPP, who will also 
implement a plan to make FBPP-owned data available to the public scientific 
research community.  Keeping the group intact, and encouraging the incorporation 
of new ideas and analyses within the scope of the FBPP goals, will take maximum 
advantage of the collaborative effort and resources already developed by the FBPP, 
and will also allow for significant contributions to advance hypertension 

The renewal as defined under this notice of limited competition will not include 
large scale recruitment of new participants or follow up clinical exams on 
existing participants.  However, renewal applications may include in depth, 
controlled clinical and/or physiological investigations in a limited number of 
selected participants.  Plans for data sharing of this unique resource will be a 
part of this renewal application 


Applications must be prepared using the PHS 398 research grant application 
instructions and forms (rev. 5/2001). Applications must have a DUN and Bradstreet 
(D&B) Data Universal Numbering System (DUNS) number as the Universal Identifier 
when applying for Federal grants or cooperative agreements. The DUNS number can be 
obtained by calling (866) 705-5711 or through the web site at The DUNS number should be entered on line 11 of 
the face page of the PHS 398 form. The PHS 398 document is available at in an interactive format.  
For further assistance contact GrantsInfo, Telephone (301) 710-0267, Email:

NHLBI will contact the current awardees regarding application procedures and 
format.  Written and telephone inquiries concerning this may be directed to:  

Dina Paltoo, Ph.D., M.P.H
Bioengineering and Genomic Applications Scientific Research Group
Division of Heart and Vascular Diseases
National Heart, Lung, and Blood Institute
Rockledge II, Room 9180, MSC 7940
6701 Rockledge Drive
Bethesda, MD 20892-7940
Telephone: (301) 435-1802
FAX: (301) 480-1336


Cashell E. Jaquish, Ph.D.
Genetic Epidemiology Scientific Research Group
Division of Epidemiology and Clinical Applications
National Heart, Lung and Blood Institute
Rockledge II, Room 8170, MSC 7934
6701 Rockledge Drive
Bethesda, MD  20892-7934
Telephone:  (301) 435-0447
FAX:  (301) 480-1455

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS) - Government Made Easy

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.