Release Date:  May 6, 2002

NOTICE:  NOT-HL-02-013

National Heart, Lung, and Blood Institute

National Institute on Drug Abuse


The National Heart, Lung, and Blood Institute (NHLBI) and the National 
Institute on Drug Abuse (NIDA) announce the availability of Administrative 
Supplements to NHLBI or NIDA grantees to facilitate the sharing of resources 
and/or the establishment of collaborations for HIV-associated disease research 
related to drug abuse, cardiovascular, pulmonary, hematological, and sleep 
disorders.  Applicants for the Administrative Supplements must have NHLBI or 
NIDA-funded grants studying one of the following: 1) cardiovascular, 
hematological, or pulmonary complications of HIV; 2) other pulmonary 
infections that frequently complicate HIV, such as tuberculosis or 
Pneumocystis carinii; or 3) drug abuse in the setting of HIV and related 
infections.  Applicants for Administrative Supplements may collaborate with 
other investigators to form a consortium in order to share resources and solve 
emerging medical issues related to HIV-associated cardiopulmonary and 
hematological complications or drug abuse in the setting of HIV infection.

There are major barriers for investigators conducting HIV-related research, 
such as access of equipment, core facilities and shared resources.  Thus, the 
NHLBI and NIDA will support, through Administrative Supplements, the 
introduction of specialized resources and equipment in their ongoing research 
programs.  Examples of items for sharing appropriate for this Administrative 
Supplement program include, but are not limited to 1) reagents, antibodies, 
tissues, and animal models; 2) specialized equipment; and 3) expertise, such 
as bioinformatics and computational services. 

Only existing R01 grants supported by NHLBI or NIDA, that focus on research 
involving HIV-related cardiovascular, hematological or pulmonary complications 
and related infectious diseases or drug abuse in the setting of HIV infection 
with at least one year of support remaining at the time of the supplemental 
award are eligible for a supplemental award under this notice.  The proposed 
research must be within the scope of the NHLBI or NIDA-funded parent study.  
Applicants may request one year of support in $25,000 increments up to a 
maximum request of $75,000 in direct costs.

NHLBI intends to commit up to $2,000,000 in FY 2002 and NIDA intends to commit 
up to $500,000 in FY 2002 to fund up to a total of 20 supplements.  This is a 
one-time announcement.  The receipt date for applications for the 
Administrative Supplements will be June 25, 2002.  The anticipated award date 
will be before September 30, 2002.  Requests must be received by the 
application receipt date; late applications will not be accepted.

To apply for an Administrative Supplement, applicants should send an original 
letter and two copies countersigned by the grantee institution's authorized 
business official to Dr. Deborah Applebaum-Bowden for grants supported by 
NHLBI, or to Dr. Jag H. Khalsa for grants supported by NIDA at the address 
listed below.  The letter, limited to 5 single-space typed pages, must 

o An abstract of the proposed use of supplemental funds and the 
relationship to the goals of the parent grant.

o A detailed description of the proposed use of supplemental funds, 
including technical expertise, resources available, and methodology.

o Expected overall impact of the requested supplement on ongoing research.

o A budget request with justification for the budget requested, including 
any equipment, software tools, reagents, animal costs, travel, and plans for 
technical service and resource sharing.

o Current contact information for the principal investigator, including 
mailing and e-mail address.

Although these descriptions should be as concise as possible, sufficient 
detail must be provided to allow determination of the merit of the requested 

Should the specific aims of the parent grant have changed since the original 
submission, a separate attachment (not included in the 5-page limit) 
containing the parent grant number, abstract, and current specific aims will 
need to be included.  Acknowledgment of receipt of the supplement letter will 
be provided by e-mail.  If the applicant has not received a response within 
ten business days, Dr. Deborah Applebaum-Bowden or Dr. Jag H. Khalsa should be 

NHLBI and NIDA will consider supplement requests from all eligible applicants. 
To be eligible for an administrative supplement, the proposed supplement must 
fall within the scope of the parent grant, and must be complete.  Requests 
will be evaluated by outside scientists with appropriate expertise.

The Review Criteria are:

o The relationship of the request to the parent grant.

o The significance of the potential impact of the supplement on ongoing 
research and the field.

o The demonstrated availability of the resources and expertise necessary 
for technical service and/or resource sharing.

o The appropriateness of the budget and documentation.

The applicant(s) will be notified of the funding decision within 3 months of 
submission.  Award decisions will be based upon the criteria provided above, 
availability of funds, and NHLBI and NIDA programmatic priorities and balance. 


Inquiries concerning this notice are strongly encouraged.  The opportunity to 
clarify any issue or questions from potential applicants is welcome.

Direct inquiries regarding programmatic issues to:

Deborah Applebaum-Bowden, Ph.D.
Division of Heart and Vascular Diseases
National Heart, Lung and Blood Institute
Two Rockledge Center, Rm 10184
6701 Rockledge Dr., MSC 7956
Bethesda, MD 20892-7956
Telephone:  (301) 435-0550
Fax:  (301) 480-2858
E-mail: applebad@nhlbi.nih.gov

Sandra Colombini Hatch, M.D.
Division of Lung Diseases
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Suite 10124, MSC 7952
Bethesda, MD 20892-7952
Telephone:  (301) 435-0222
FAX:  (301) 480-3557
E-mail:  hatchs@nhlbi.nih.gov

Luiz Barbosa, D.V.M.  
Division of Blood Diseases and Resources
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Room 10146, MSC 7950
Bethesda, MD 20892-7950
Telephone:  (301) 435-0075
FAX:  (301) 480-0868
E-mail: BarbosaL@nhlbi.nih.gov

Jag H. Khalsa, Ph.D.
Center on AIDS and Other Medical
 Consequences of Drug Abuse (CAMCODA)
National Institute on Drug Abuse (NIDA)
6001 Executive Blvd., room 5198, MSC 9593
Bethesda, MD 20892-9593
Telephone:  (301) 443-1801
Fax:  (301) 594-6566
E-mail: jk98p@nih.gov
Direct inquiries regarding fiscal matters to:

Raymond L. Zimmerman
Grants Operations Branch
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Room 7156, MSC 7926
Bethesda, MD 20892-7926
Telephone:  (301) 435-0171
FAX:  (301) 480-3310
E-mail:  ZimmermR@nhlbi.nih.gov

Gary Fleming, J.D., M.A.
Grants Management Branch
National Institute on Drug Abuse
6001 Executive Blvd., Room 3131, MSC 9541
Bethesda, MD 20892-9541
Telephone:  (301) 443-6710
FAX :  (301) 594-6847
E-mail: gf6s@nih.gov

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