Notice of Intent to Publish a Notice of Funding Opportunity for Broadening Opportunities for Computational Genomics and Data Science Education (UE5 – Clinical Trial Not Allowed)
Notice Number:

Key Dates

Release Date:
May 30, 2023
Estimated Publication Date of Notice of Funding Opportunity :
August 07, 2023
First Estimated Application Due Date:
October 10, 2023
Earliest Estimated Award Date:
September 01, 2024
Earliest Estimated Start Date:
September 01, 2024
Related Announcements

May 10, 2022 - Educational Hub for Enhancing Diversity in Computational Genomics and Data Science (U24 Clinical Trials Not Allowed) . See RFA-HG-22-002:

Issued by

National Human Genome Research Institute (NHGRI)


The National Human Genome Research Institute intends to issue a Notice of Funding Opportunity (NOFO) to solicit applications to support educational activities that encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences (see Notice of NIH's Interest in Diversity, NOT-OD-20-031) , to pursue further studies or careers in computational genomics and data science research.

The intended NOFO will be based on a concept recently approved by the National Advisory Council on Human Genome Research and accompanying discussion.

This Notice is being provided to allow potential applicants sufficient time to develop responsive projects.

The NOFO is expected to be published in the summer of 2023 with an expected application due date in the fall of 2023.

This NOFO will utilize the UE5 activity code. Details of the planned NOFO are provided below.

Research Initiative Details

The goal of the intended NOFO is to support faculty members at institutions with a mission to serve historically underrepresented populations in biomedical research to develop undergraduate and master’s degree-level educational content in computational genomics, data science, or a combination of these topics. Content developed will be expected to leverage the resources of NIH cloud computing platforms such as NHGRI’s AnVIL and the All of Us Researcher Workbench.

The intended NOFO is a parallel effort to the Educational Hub for Enhancing Diversity in Computational Genomics and Data Science (hereafter called the CGDS Hub) described in detail in RFA-HG-22-002. Recipients of this NOFO will be expected to make use of educational support resources developed by the CGDS Hub.

Specifically, the intended NOFO will support the development of undergraduate and master’s degree-level educational content related to computational genomics, data science, cloud computing, or a combination of these topics, tailored towards students attending institutions with a mission to serve historically underrepresented populations in biomedical research.

For the intended NOFO, “educational content” is defined as material designed for classroom, virtual, or hybrid delivery for teaching computational genomics and data science topics to students at the undergraduate and master’s degree levels. This could include (but is not limited to) elements such as classroom lectures, instructional videos, interactive demonstrations, and practicum exercises that encourage and enable self-learning. Components of the educational content that involve data analysis will be expected to make substantial use of cloud computing platforms in the form of students completing data analysis exercises through cloud user accounts on NIH-supported cloud computing platforms. Use of non-cloud web servers, software installed on student computers or institutional high-performance computing servers is not covered by the scope of this NOFO.

Beyond individual awards to applicant institutions, the intended NOFO also has a broader objective to create a community of institutions interested in working collectively to define, develop, and test content integrating computational genomics and data science into their existing biomedical science curricula.

As a complement to classroom and cloud-based educational content development, the intended NOFO will also support opportunities for students to participate in hands-on research projects. Specifically, in FY26 and FY27, the CGDS Hub will administer a competitive opportunity for recipients of the intended NOFO to receive support for hands-on student research projects in genomics and data science.

Funding Information

Estimated Total Funding


Expected Number of Awards


Estimated Award Ceiling

$150,000 direct cost per year for five years

Primary Assistance Listing Number(s)


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time. 

Anticipated Eligible Organizations: To be eligible for the intended NOFO, the applicant institution must be a domestic institution located in the United States and its territories which: ? Has received an average of less than $10 million per year of R01 total cost of NIH support for the past three fiscal years, and; ? Awards undergraduate or master’s degrees in biomedical sciences, and; ? Has a documented historical and current mission to educate students from any of the populations that have been identified as underrepresented in biomedical research as defined by the National Science Foundation NSF, see (i.e., African Americans or Blacks, Hispanic or Latino Americans, American Indians, Alaska Natives, Native Hawaiians, U.S. Pacific Islanders, and persons with disabilities) or has a documented record of recruiting, training and/or educating, and graduating underrepresented students as defined by NSF (see above), which has resulted in increasing the institution's contribution to the national pool of graduates from underrepresented backgrounds who pursue biomedical research careers.


Please direct all inquiries to:

Shurjo K. Sen, Ph.D.
National Human Genome Research Institute (NHGRI)
Telephone: 301-827-7028