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NOT-HG-21-010 - Notice of Special Interest (NOSI): Clarification of the Objectives and Program Elements in NHGRI Applications Submitted in Response to the "Ruth L. Kirschstein NRSA Institutional Research Training Grants (Parent T32)"

Issued by

National Human Genome Research Institute (NHGRI)

Purpose

Purpose

The purpose of this Notice is to clarify the requirement of advance approval from NHGRI to submit Parent T32 Applications requesting $500,000 or greater in direct costs in NOT-HG-21-010, “Notice of Special Interest (NOSI): Clarification of the Objectives and Program Elements in NHGRI Applications Submitted in Response to the "Ruth L. Kirschstein NRSA Institutional Research Training Grants (Parent T32)".”

The requirement for advance approval to submit a T32 application with a budget exceeding $500,000 or greater has been removed.

Currently Reads:

Overall Considerations:

• In general, NHGRI does not expect to make more than one award per institution per training track - genome sciences, genomic medicine and ELSI. Institutions that already have an award in one of these three areas are encouraged to apply for an award in a different area. Institutions that have more than one NHGRI-supported R25 diversity program and/or T32 program must demonstrate coordination and collaboration amongst the programs.

• Preference is to support one career level only per T32 program (pre-doctoral or post-doctoral). For applicants who propose to provide training at both the pre-doctoral and post-doctoral levels, a detailed training plan must be provided for each level. Applicants should demonstrate coordination and collaboration such that there is synergy among the trainee cohort.
• Training programs should be housed in institutions that have significant support from NHGRI.
• A letter must be submitted and approved by the NHGRI Scientific Contact listed below in advance if your application will request $500,000 or more in direct costs. If approved, the applicant must include a cover letter with the application indicating NHGRI acceptance.
• The number of trainee slots awarded will depend upon the quality of the proposed program as determined by peer review, programmatic considerations, and the availability of funds.
• Trainees should be appointed for a minimum of two years and no more than three.
• For subsequent training, trainees are strongly encouraged to take advantage of the NRSA Individual Pre-doctoral (F31) or NRSA Individual Post-doctoral (F32) fellowship programs or the Mentored Career Development Awards (K01, K08) or the NIH Pathway to Independence Award (K99/R00) programs, as appropriate.

Modified to Read:

Overall Considerations:

• In general, NHGRI does not expect to make more than one award per institution per training track - genome sciences, genomic medicine and ELSI. Institutions that already have an award in one of these three areas are encouraged to apply for an award in a different area. Institutions that have more than one NHGRI-supported R25 diversity program and/or T32 program must demonstrate coordination and collaboration amongst the programs.
• Preference is to support one career level only per T32 program (pre-doctoral or post-doctoral). For applicants who propose to provide training at both the pre-doctoral and post-doctoral levels, a detailed training plan must be provided for each level. Applicants should demonstrate coordination and collaboration such that there is synergy among the trainee cohort.

• Training programs should be housed in institutions that have significant support from NHGRI.
• The number of trainee slots awarded will depend upon the quality of the proposed program as determined by peer review, programmatic considerations, and the availability of funds.
• Trainees should be appointed for a minimum of two years and no more than three.
• For subsequent training, trainees are strongly encouraged to take advantage of the NRSA Individual Pre-doctoral (F31),NRSA F31 to promote diversity or NRSA Individual Post-doctoral (F32) fellowship programs or the Mentored Career Development Awards (K01, K08) or the NIH Pathway to Independence Award (K99/R00) programs, as appropriate.

All other aspects of this NOSI remain unchanged.

Inquiries

Please direct all inquiries to:

Lucia A. Hindorff, PhD, MPH
National Human Genome Research Institute
Telephone: (240) 271-1509
Email: hindorffl@mail.nih.gov