Key Dates

Related Announcements

• February 15, 2024 - Notice of Participation of NIMH in PAR-23-199, "ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed). See Notice NOT-MH-24-195.
• June 6, 2023 - ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed). See NOFO PAR-23-199.

Issued by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Purpose

The purpose of this notice is to correct an error in the Research Strategy instructions for PAR-23-199 ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed) regarding the requirements around eRA Commons IDs.  All personnel listed on the R&R Senior/Key Person Profile form, including Senior/Key Personnel as well as Other Significant Contributors (see definitions in the NIH Grants Policy Statement (NIH GPS 1.2)), are required to have an eRA Commons ID, as clarified in NOT-OD-24-042.  This means that all members of the proposed Gene and/or Variant Curation Expert Panel(s) need an eRA Commons ID so that their NIH biosketch can be included in the application.  If a member of the Expert Panel does not have an eRA Commons ID, then applicants will encounter an eRA system error that prevents submission of their application to NIH.  Applicants are encouraged to verify whether any Expert Panel members need to request an eRA Commons ID well in advance of the receipt date.

The following sections of the notice of funding opportunity (NOFO) have been revised: 

Section IV. Application and Submission Information

2. Content and Form of Application Submission

SF424(R&R) Senior/Key Person Profile

Currently reads:

All instructions in the SF424 (R&R) Application Guide must be followed.

Section IV. Application and Submission Information

2. Content and Form of Application Submission

SF424(R&R) Senior/Key Person Profile

Modified to read (changes are bold and underlined):

All instructions in the SF424 (R&R) Application Guide must be followed.

Each member of the Expert Panel must be listed as either Senior/Key Personnel or as Other Significant Contributors under personnel on the R&R Senior/Key Person Profile Form in order to submit their NIH biosketch.


Section IV. Application and Submission Information

2. Content and Form of Application Submission

Research Strategy

Currently reads:

2. Describe the leadership (including a chair and co-chair, if needed) and membership of the Expert Panel as well as other key group members, including a project coordinator and clinical and informatics curators who will provide support for the Expert Panel. Describe the membership of the Expert Panel that will select and evaluate the clinical relevance of genes/variants to be curated. Include details about how each member will contribute to establishing the clinical actionability of the genes/variants being curated.

Each member of the Expert Panel should be listed under personnel as consultants with an NIH biosketch attached. Consultants do not require an e-commons name and should only be paid nominal fees.

Section IV. Application and Submission Information

2. Content and Form of Application Submission

Research Strategy

Modified to read (changes are bold and underlined):

2. Describe the leadership (including a chair and co-chair, if needed) and membership of the Expert Panel as well as other key group members, including a project coordinator and clinical and informatics curators who will provide support for the Expert Panel. Describe the membership of the Expert Panel that will select and evaluate the clinical relevance of genes/variants to be curated. Include details about how each member will contribute to establishing the clinical actionability of the genes/variants being curated.

Each member of the Expert Panel is required to be listed in the Senior/Key Person profile form and submit an NIH biosketch, which requires having an eRA Commons ID.  Expert Panel members should only be paid nominal fees.

All other aspects of PAR-23-199 remain unchanged.

Inquiries

Please direct all inquiries to:

Mollie Minear, PhD
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Email: mollie.minear@nih.gov