Notice Number: NOT-HD-20-008
Release Date: April 6, 2020
First Available Due Date: June 01, 2020
Expiration Date: May 02, 2022
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute on Minority Health and Health Disparities (NIMHD)
National Cancer Institute (NCI)
National Institute of Environmental Health Sciences ( NIEHS )
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Reproductive health is a fundamental aspect of overall human health and wellbeing, but research on reproductive health is not always integrated into large and/or longitudinal studies of other systems. For the purposes of this notice, “reproductive health” includes fertility/infertility and gynecologic or andrologic health for those attempting to conceive, not attempting to conceive, or actively preventing pregnancy. Reflecting the importance of research in these areas, NICHD has laid out “Promoting Gynecologic, Andrologic, and Reproductive Health” as a major theme of the new NICHD Strategic Plan 2020.
The ultimate goal of this NOSI is to improve human reproductive health by supporting the addition of reproductive health components to ongoing large and/or longitudinal studies that have not previously collected data or specimens relevant to reproductive health on a large-scale basis. It is anticipated that this mechanism will allow the collection of data and biospecimens from large and/or long-running studies that will enable researchers to address reproductive questions that would otherwise require independent cohorts.
These components may include new survey questions, measures, or protocols to support the collection of relevant biological data or specimens that can be used for future analyses of reproductive health outcomes. The addition of these components to ongoing projects is expected to encourage interdisciplinary collaborations between the investigators of the ongoing studies and reproductive health researchers, expanding the potential scientific insight and investigational toolkit available to these projects and the field.
This initiative requires that the projects address topics or questions that are directly relevant to the NICHD Strategic Plan 2020 and one or more of the research interests of the following branches at NICHD (description of the mission and high priority areas for each participating branch are linked, below) and that address the:
Funding priority will be given to supplement applications whose parent award does not currently include a reproductive health aim. Projects that examine reproductive health questions in diverse populations in order to address health disparities are encouraged. In addition, all applications should include 1) a reproductive health expert as key personnel with a project management plan similar to an MPI leadership plan and 2) a data and resource sharing plan.
Projects of high priority for this FOA include, but are not limited to:
Projects of lower priority for this FOA include, but are not limited to:
Applications that propose supplemental data collection in on-going studies should clearly address the following: study progress, including enrollment, to date, the anticipated number of data points that can be captured with the proposed supplemental assessments, and a plan for how the proposed reproductive health data will be analyzed.
Applications that propose new measures and assessment of reproductive outcomes should:
Applications that propose collection of new or additional biospecimens should include a biospecimen resource sharing plan that addresses the following:
Biospecimens that might be collected under this FOA could include saliva, blood, semen, endometrial biopsy, cervical mucus, and menstrual effluent, among other sample types. The biospecimen sharing plans will be used in the review and prioritization of received applications.
Application and Submission Information
Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.
Eligibility: The scope of this FOA is limited to parent awards focused on clinical research (human subjects research, clinical trials not required). Studies of model systems will be considered non-responsive. Administrative supplements can be sought through all non-training grant mechanisms, including small business innovation research and technology transfer applications. Parent awards focused on reproductive health will not be eligible for this administrative supplement.
Award Duration: Award duration is, at minimum, one year and limited to the remaining duration of the parent award. Active awards with project end dates in FY 2021 or later are eligible. The award may not be in terminal no cost extension or going into no cost extension in FY2020. Please note that a few ICs limit no cost extensions in a non-competing year of an award. For that reason, it is important to contact staff at the Institute supporting the award when planning the duration of the supplement request.
Award Budget: Total costs for a supplement application cannot exceed $250,000.
Institute-, Center-, and Office-specific Instructions
NIMHD is interested in projects that focus on one or more NIH-designated U.S. health disparity populations, which include Blacks or African Americans, Hispanics or Latinos, American Indians and Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities. Comparison groups may be included as appropriate for the research questions posed.
NICHD will conduct administrative reviews of all supplement applications based on initial review from their parent award IC. NICHD will make funds available for at least two awards from across all participating ICs.
Please direct all inquiries to the contacts in Section VII of the listed funding opportunity announcements with the following additions/substitutions:
Candace Tingen, PhD
National Institute of Child Health and Human Development (NICHD)
Melissa Smarr, PhD
National Institute of Environmental Health Sciences (NIEHS)