Notice Number: NOT-HD-18-004

Key Dates
Release Date: February 13, 2018

Issued by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Purpose

The purpose of this Notice is to inform potential applicants that the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is participating in PAR-18-411 "Getting To Zero: Understanding HIV Viral Suppression and Transmission in the United States (R01 Clinical Trial Not Allowed)".

The following sections have been updated to reflect the participation of NICHD in this FOA:

Part 1. Overview Information
Components of Participating Organizations
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Mental Health (NIMH)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Catalog of Federal Domestic Assistance (CFDA) Number(s)
93.855; 93.242; 93.865

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

NICHD is particularly interested in research among adolescents and young adults, 12-24 years old, that supports:

• Improved accuracy and speed to describe the epidemiology of HIV care indicators among adolescents and young adults: testing, linkage, engagement, retention, ART uptake, suppression of viral load at a jurisdictional or national population level.
• Evaluations of the epidemiology of HIV care to monitor progress overall and in sub-populations of adolescents and young adults, such as by gender, transmission risk, race, age, developmental stage or geographic region (e.g. phylogenetic and geospacial analyses of HIV transmission dynamics).
• Research to uncover novel correlates and predictors of initial and sustained HIV viral suppression capitalizing on a rich understanding of the contextual factors specific to adolescents and young adults impacting suppression.
• Measurements of long-term viral suppression, and the correlates and predictors of success in adolescents and young adults.
• Implementation strategies addressing coverage, service delivery systems, barriers to service delivery and uptake, and stigma that can be obtained from existing data or estimated in modeling applications and including vulnerable adolescent periods of transition to adult service providers.
• Innovative strategies harnessing Big Data Science and related technologies to improve and expedite viral suppression among hard to reach populations such as adolescents who are unaware they are infected, repeatedly disengage and re-engage in care, use substances or suffer from mental illness or are unstably housed (e.g. mobile engagement strategies, virtual cohorts).

Part 2. Section VII. Agency Contacts

Scientific/Research Contact(s)
Bill G. Kapogiannis, M.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301-402-0698
Email: [email protected]

Financial/Grants Management Contact(s)
Bryan S. Clark, MBA
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301-435-6975
Email: [email protected]

All other aspects of this FOA remain unchanged.

Inquiries

Please direct all inquiries to:

Bill G. Kapogiannis, M.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301-402-0698
Email: [email protected]