Notice Number: NOT-HD-17-023

Key Dates
Release Date: August 15, 2017

PAR-17-313

Issued by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Purpose

The purpose of this Notice is to inform potential applicants that the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) will participate, effective immediately, in PAR-17-313, “Global Brain and Nervous System Disorders Research Across the Lifespan (R21).

Part 1. Overview Information

Components of Participating Organizations
Fogarty International Center (FIC)
National Institute on Aging (NIA)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute on Environmental Health Sciences (NIEHS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
Office of Dietary Supplements (ODS)
National Eye Institute (NEI)
National Institute of Dental and Craniofacial Research (NIDCR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Catalog of Federal Domestic Assistance (CFDA) Number(s)
93.121, 93.989, 93.866, 93.113, 93.321, 93.853, 93.867, 93.173, 93.242, 93.865  

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

The following includes NICHD priorities for brain and nervous system disorders research in LMICs:

• Integrated research studies to determine how nutritional and inflammatory status, independently and in relationship with each other, impact brain and neurodevelopment from preconception through gestation, infancy, childhood, adolescence, and beyond, and what interventions can favorably alter these processes. These can also include holistic interventions that consider the child's physical and social environment.
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• Emerging and growing research areas such as genomics, epigenetics, sleep, and the microbiome on child nutrition, inflammation and their impact on neurodevelopment.
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• Develop standardized norms for neurodevelopment and new tools for assessment and monitoring of various influences in child brain development, including more precise biomarkers for neurodevelopmental deficits or disorders resulting from early environmental stressors or adversity.
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• Research on the impact of prematurity on brain development.
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• Interaction of environmental enteropathy and infectious diseases (e.g. HIV, malaria, tuberculosis and Zika virus) with brain development in the fetus, infants, children and adolescents in LMICs.
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• The role of and mechanisms through which non-infectious inflammation (e.g., chronic diseases, exposure to environmental toxins, and psychological stress) impacts neurodevelopment.
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• Development of field-friendly, brain-based measures for resource-limited settings that can meaningfully assess multiple domains in the infant and young child and yield predictive value for later function
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• Identify exposures, influences, and interventions that contribute to neurodevelopmental resiliency.
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• Natural history and neurobiological and behavioral transitions for children with neurodevelopmental disorders.

Part 2. Section VII. Agency Contacts

Scientific/Research Contact(s)

Danuta Krotoski, PhD
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301 496-5576
Email: krotoskd@mail.nih.gov

Financial/Grants Management Contact(s)
Bryan Clark, MBA
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301-435-6925
Email: clarkb1@mail.nih.gov
  
All other aspects of this FOA remain unchanged.

Inquiries

Please direct all inquiries to:

Danuta Krotoski, PhD
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301 496-5576
Email: krotoskd@mail.nih.gov