Notice of Special Interest (NOSI): Supporting Women’s Health Research in the IDeA States through the Centers of Biomedical Research Excellence (COBRE) Phase I Program
Notice Number:

Key Dates

Release Date:

August 26, 2021

First Available Due Date:
January 27, 2022
Expiration Date:
January 28, 2022

Related Announcements

PAR-19-313 - Centers of Biomedical Research Excellence (COBRE) Phase 1 (P20 Clinical Trial Optional)

Issued by

National Institute of General Medical Sciences (NIGMS)

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

Office of Research on Women's Health (ORWH)


The purpose of this Notice of Special Interest (NOSI) is to inform potential applicants of the National Institutes of Health’s interest in supporting women’s health research in Institutional Development Award (IDeA)-eligible states through PAR-19-313 "Centers of Biomedical Research Excellence (COBRE) Phase 1 (P20 Clinical Trial Optional)".

Research Objectives

Women and children in IDeA states often have less access to health care and suffer from poorer health outcomes compared with other Americans. Several IDeA states are among the states with the highest maternal and infant mortality rates in the US. Therefore, the Office of Research on Women's Health (ORWH), which coordinates women’s health research across the NIH, intends to support one COBRE award that advances women’s health research and expands the research capacity in IDeA states in this scientific area.

ORWH’s vision is to advance biomedical research where sex and/or gender influences are integrated into the biomedical research enterprise and every woman receives evidence-based disease prevention and treatment tailored to her own needs, circumstances, and goals.

The proposed research must address at least one of the strategic goals of the Trans-NIH Strategic Plan for Women's Health Research "Advancing Science for the Health of Women" to advance rigorous research relevant to the health of women, foster innovation, expand emerging areas of science, and address women’s health issues of public importance. Research to improve the health of women requires a comprehensive consideration of the many factors that influence women’s health, such as sex and gender, race and ethnicity, and a host of other internal and external factors. ORWH encourages research across the lifespan and on a wide range of research relevant to women's health.

Application and Submission Information

This Notice applies to the January 27, 2022 due date.

Applications for this initiative must be submitted to and be in full compliance with the following funding opportunity announcement (FOA):

  • PAR-19-313 - Centers of Biomedical Research Excellence (COBRE) Phase 1 (P20 Clinical Trial Optional).

All instructions in the SF424 (R&R) Application Guide and the funding opportunity announcement used for submission must be followed, with the following additions:

  • For funding consideration, applicants must include “NOT-GM-21-056” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative.

Applications nonresponsive to terms of this NOSI will be withdrawn from consideration for this initiative.


Please direct all inquiries to the contacts in Section VII of the listed funding opportunity announcements with the following additions/substitutions:

Crina Frincu, Ph.D.
National Institute of General Medical Sciences (NIGMS)

Regine A. Douthard, M.D., MPH
NIH Office of Research on Women’s Health Research (ORWH)

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices